ArticleSocial psychiatry and psychiatric epidemiology2014
Insight and attitudes towards medication among inpatients with chronic schizophrenia in the US and China.
Article in Social psychiatry and psychiatric epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Impaired insight in schizophrenia: impact on patient-reported and physician-reported outcome measures in a randomized controlled trial.BMC psychiatry · 2022Trial
- Predicting Physical Aggression among Schizophrenia Patients in Rural Communities of Southwestern China.Alpha psychiatry · 2025Article
- Attitude towards mental help-seeking, motivation, and economic resources in connection with positive, negative, and general psychopathological symptoms of schizophrenia: a pilot study of a psychoeducation program.Frontiers in psychiatry · 2024Article
- Initial attitudes toward a drug predict medication adherence in first-episode patients with schizophrenia: a 1-year prospective study in China.BMC psychiatry · 2023Article
- Why did China's mental health law have a limited effect on decreasing rates of involuntary hospitalization?International journal of mental health systems · 2022Article
- Habits and Attitudes of Video Gaming and Information Technology Use in People with Schizophrenia: Cross-Sectional Survey.Journal of medical Internet research · 2020Article
- Brain function differences in drug-naïve first-episode auditory verbal hallucination-schizophrenia patients with versus without insight.Chinese medical journal · 2019Article
- Article
- Comparison of Olanzapine versus Other Second-Generation Antipsychotics in the Improvement of Insight and Medication Discontinuation Rate in Schizophrenia.Shanghai archives of psychiatry · 2018Article
- Insight, self-stigma and psychosocial outcomes in Schizophrenia: a structural equation modelling approach.Epidemiology and psychiatric sciences · 2018Article
- Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2018Article
- Effect of a Multi-Dimensional and Inter-Sectoral Intervention on the Adherence of Psychiatric Patients.PloS one · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe impact of culture on insight on illness and attitudes towards medication among patients with schizophrenia has not been well studied. We compared inpatients in the US and in China (a culture that numerous studies have shown heavily stigmatizes mental illness and psychosis), on measures of insight and acceptance of medication, controlling for overall severity of schizophrenia symptoms.
methodsClinical antipsychotic treatment for intervention effectiveness (CATIE) was a large study of pharmacotherapy of people with schizophrenia across the US. Insight was measured using the insight and treatment attitudes questionnaire (ITAQ) and attitudes towards medication by the drug attitude inventory (DAI) and symptoms of schizophrenia by the Positive and Negative Syndrome Scale (PANSS). These measures were applied to a sample of hospitalized patients diagnosed with schizophrenia at the Guangzhou Psychiatric hospital, the largest psychiatric hospital in Southern China. Mean ITAQ and DAI scores, net of total schizophrenia symptoms and other differences were compared at the time of admission using analysis of covariance.
resultsBoth insight and favourable attitudes towards medication were significantly and substantially lower in the sample from Guangzhou on bivariate analysis even after adjusting for severity of overall schizophrenia symptoms on the PANSS.
conclusionInpatients in China had far lower scores on measures of insight and acceptance of their need for and benefits of medication, controlling for overall severity of schizophrenia symptoms, suggesting a significant impact of Chinese culture which is presumed to more heavily stigmatize mental illness and especially psychosis, although other explanations can not be ruled out.
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