Evidence map›Paper›PMID 24549678›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2014

Global protein-RNA interaction mapping at single nucleotide resolution by iCLIP-seq.

Chengguo Yao, Lingjie Weng, Yongsheng Shi

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Specific Regulation of mGenomics, proteomics & bioinformatics · 2023
    Article
  4. Regulation of bacterial virulence by Csr (Rsm) systems.Microbiology and molecular biology reviews : MMBR · 2015
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chengguo YaoDepartment of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.
Lingjie Weng
Yongsheng Shi

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Christine Hui · 1994 to 2026
$57.9M
Characterization of the mammalian mRNA-3'-end processing complexR01GM090056 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI SHI, YONGSHENG · 2010 to 2022
$4.2M
HSRD VA CDP 12-186NCI NIH HHS P30 CA062203NIGMS NIH HHS R01 GM090056NIGMS NIH HHS R01GM090056
6 · The paper itself

Abstract

Eukaryotic genomes encode a large number of RNA-binding proteins, which play critical roles in many aspects of gene regulation. To functionally characterize these proteins, a key step is to map their interactions with target RNAs. UV crosslinking and immunoprecipitation coupled with high-throughput sequencing has become the standard method for this purpose. Here we describe the detailed procedure that we have used to characterize the protein-RNA interactions of the mRNA 3' processing factors.

Indexed as

Binding SitesEukaryotaGenomeHigh-Throughput Nucleotide SequencingImmunoprecipitationMolecular BiologyRNARNA-Binding ProteinsRNARNA-Binding Proteins

Identifiers

PMID24549678
PMCPMC4412157

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.