ArticleJournal of biomedical optics2014
Anthropomorphic breast phantoms with physiological water, lipid, and hemoglobin content for near-infrared spectral tomography.
Article in Journal of biomedical optics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Optical phantoms for the characterization and validation of imaging and spectroscopy: a review.Biophotonics discovery · 2026Review
- Establishing the feasibility and reliability of broadband absorption spectroscopy for measuring cerebral water content in adults.Biomedical optics express · 2025Article
- Solid breast tumors phantom emulating oxy and deoxyhemoglobin concentrations for near infrared imaging.PloS one · 2025Article
- Development of a platform for broadband, spectra-fitted, tissue optical phantoms.Journal of biomedical optics · 2023Article
- Tissue-mimicking phantom materials with tunable optical properties suitable for assessment of diffuse reflectance spectroscopy during electrosurgery.Biomedical optics express · 2022Article
- Best practices for fNIRS publications.Neurophotonics · 2021Article
- Stable tissue-simulating phantoms with various water and lipid contents for diffuse optical spectroscopy.Biomedical optics express · 2018Article
- Breast density quantification using structured-light-based diffuse optical tomography simulations.Applied optics · 2017Article
- Solid tissue simulating phantoms having absorption at 970 nm for diffuse optics.Journal of biomedical optics · 2017Article
- Three-dimensional printed optical phantoms with customized absorption and scattering properties.Biomedical optics express · 2015Article
- Next-generation Raman tomography instrument for non-invasive in vivo bone imaging.Biomedical optics express · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Breast mimicking tissue optical phantoms with sufficient structural integrity to be deployed as stand-alone imaging targets are developed and successfully constructed with biologically relevant concentrations of water, lipid, and blood. The results show excellent material homogeneity and reproducibility with inter- and intraphantom variability of 3.5 and 3.8%, respectively, for water and lipid concentrations ranging from 15 to 85%. The phantoms were long-lasting and exhibited water and lipid fractions that were consistent to within 5% of their original content when measured 2 weeks after creation. A breast-shaped three-compartment model of adipose, fibroglandular, and malignant tissues was created with water content ranging from 30% for the adipose simulant to 80% for the tumor. Mean measured water content ranged from 30% in simulated adipose to 73% in simulated tumor with the higher water localized to the tumor-like material. This novel heterogeneous phantom design is composed of physiologically relevant concentrations of the major optical absorbers in the breast in the near-infrared wavelengths that should significantly improve imaging system characterization and optimization because the materials have stand-alone structural integrity and can be readily molded into the sizes and shapes of tissues commensurate with clinical breast imaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.