ArticleScientific reports2014
Understanding the antimicrobial mechanism of TiO₂-based nanocomposite films in a pathogenic bacterium.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
99 citing papers in PubMed, 1 synthesis or guideline pooled it, 418 citations in OpenAlex.
- Titanium dioxide nanoparticles: revealing the mechanisms underlying hepatotoxicity and effects in the gut microbiota.Archives of toxicology · 2023Pooled it
- Microbial Aerosols in Livestock Farming Environment: A Threat That Cannot Be Ignored.Veterinary sciences · 2025Review
- Application of TiOInternational journal of molecular sciences · 2025Review
- Multifunctional Cyclic Olefin Copolymer-Titanium Dioxide-Based Nanocomposites for Enhanced Antibacterial and Biocompatible Properties.ACS omega · 2025Article
- Enhancing the Antimicrobial and UV Resistance Properties of PC Blend and Recycled Cotton Fabric through Ag/TiOACS omega · 2025Article
- Staphylococcal Drug Resistance: Mechanisms, Therapies, and Nanoparticle Interventions.Infection and drug resistance · 2025Review
- Role of metal nanomaterials in wound healing - a review.Frontiers in bioengineering and biotechnology · 2025Review
- Titanium dioxide nanoparticles: a promising candidate for wound healing applications.Burns & trauma · 2025Review
- Unlocking the potential of titanium dioxide nanoparticles: an insight into green synthesis, optimizations, characterizations, and multifunctional applications.Microbial cell factories · 2024Review
- Fabrication and assessment of performance of clay based ceramic membranes impregnated with CNTs in dye removal.Scientific reports · 2024Article
- Expediting the bioactivity of zinc sulfide nanoparticles with copper oxide as a nanocomposite.BMC chemistry · 2024Article
- Antibiofilm Activity of PDMS/TiOACS omega · 2024Article
- Review of Antimicrobial Properties of Titanium Dioxide Nanoparticles.International journal of molecular sciences · 2024Review
- The progress and future of the treatment of Candida albicans infections based on nanotechnology.Journal of nanobiotechnology · 2024Review
- Article
- Light-Assisted 3D-Printed Hydrogels for Antibacterial Applications.Small science · 2024Article
- Antimicrobial Activity againstACS omega · 2024Article
- Physicochemical methods for disinfection of contaminated surfaces - a way to control infectious diseases.Journal of environmental health science & engineering · 2024Review
- Using biologically synthesized TiOScientific reports · 2023Article
- Synthesis and characterization of TiOBMC microbiology · 2023Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Titania (TiO₂)-based nanocomposites subjected to light excitation are remarkably effective in eliciting microbial death. However, the mechanism by which these materials induce microbial death and the effects that they have on microbes are poorly understood. Here, we assess the low dose radical-mediated TiO₂ photocatalytic action of such nanocomposites and evaluate the genome/proteome-wide expression profiles of Pseudomonas aeruginosa PAO1 cells after two minutes of intervention. The results indicate that the impact on the gene-wide flux distribution and metabolism is moderate in the analysed time span. Rather, the photocatalytic action triggers the decreased expression of a large array of genes/proteins specific for regulatory, signalling and growth functions in parallel with subsequent selective effects on ion homeostasis, coenzyme-independent respiration and cell wall structure. The present work provides the first solid foundation for the biocidal action of titania and may have an impact on the design of highly active photobiocidal nanomaterials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.