ReviewMarine drugs2014
The lipopolysaccharide export pathway in Escherichia coli: structure, organization and regulated assembly of the Lpt machinery.
Review in Marine drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 49 citations in OpenAlex.
- A review on hypervirulent and multidrug-resistant Klebsiella pneumoniae: An emerging threat to human health.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Molecular mechanism of action of small molecule SMT-738 on bacterial lipoprotein transporter LolCDE.Nature communications · 2026Article
- Novel microbiotaFrontiers in microbiology · 2024Article
- Article
- Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth.PLoS genetics · 2021Article
- Transcriptomic Reprograming ofPlants (Basel, Switzerland) · 2021Article
- Host-Pathogen Interactions betweenMicroorganisms · 2020Article
- Isolation of Anti-Inflammatory and Epithelium ReinforcingNutrients · 2020Article
- The protective effect of icariin and phosphorylated icariin against LPS-induced intestinal goblet cell dysfunction.Innate immunity · 2020Article
- Visible-Light Active Titanium Dioxide Nanomaterials with Bactericidal Properties.Nanomaterials (Basel, Switzerland) · 2020Review
- Genome Insights into the Novel SpeciesMicroorganisms · 2019Article
- Comparative bioinformatic and proteomic approaches to evaluate the outer membrane proteome of the fish pathogen Yersinia ruckeri.Journal of proteomics · 2019Article
- Genome-Guided Characterization ofInternational journal of environmental research and public health · 2018Article
- Article
- Interaction of lipopolysaccharides at intermolecular sites of the periplasmic Lpt transport assembly.Scientific reports · 2017Article
- Some Gram-negative Lipoproteins Keep Their Surface Topology When Transplanted from One Species to Another and Deliver Foreign Polypeptides to the Bacterial Surface.Molecular & cellular proteomics : MCP · 2017Article
- SDS-PAGE Analysis of the Outer Membrane Proteins of Uropathogenic Escherichia coli Isolated from Patients in Different Wards of Nemazee Hospital, Shiraz, Iran.Iranian journal of medical sciences · 2016Article
- Phylogenomic analysis supports the ancestral presence of LPS-outer membranes in the Firmicutes.eLife · 2016Article
- The Klebsiella pneumoniae O12 ATP-binding Cassette (ABC) Transporter Recognizes the Terminal Residue of Its O-antigen Polysaccharide Substrate.The Journal of biological chemistry · 2016Article
- Mucosal Prevalence and Interactions with the Epithelium Indicate Commensalism ofFrontiers in microbiology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The bacterial outer membrane (OM) is a peculiar biological structure with a unique composition that contributes significantly to the fitness of Gram-negative bacteria in hostile environments. OM components are all synthesized in the cytosol and must, then, be transported efficiently across three compartments to the cell surface. Lipopolysaccharide (LPS) is a unique glycolipid that paves the outer leaflet of the OM. Transport of this complex molecule poses several problems to the cells due to its amphipatic nature. In this review, the multiprotein machinery devoted to LPS transport to the OM is discussed together with the challenges associated with this process and the solutions that cells have evolved to address the problem of LPS biogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.