Evidence map›Paper›PMID 24548922›Full record

ArticleJournal of chromatography. B, Analytical technologies in the biomedical and life sciences2014

A versatile ultra-high performance LC-MS method for lipid profiling.

Oskar L Knittelfelder, Bernd P Weberhofer, Thomas O Eichmann, Sepp D Kohlwein, Gerald N Rechberger

Abstract read
In one paragraph

Article in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

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  19. Peroxisomal Fatty Acid Oxidation and Glycolysis Are Triggered in Mouse Models of Lesional Atopic Dermatitis.JID innovations : skin science from molecules to population health · 2021
    Article
  20. HIGH RESOLUTION MASS SPECTROMETRY IN LIPIDOMICS.Mass spectrometry reviews · 2021
    Review

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oskar L KnittelfelderInstitute of Molecular Biosciences, University of Graz, Humboldtstraße 50/II, 8010 Graz, Austria.
Bernd P WeberhoferInstitute of Molecular Biosciences, University of Graz, Humboldtstraße 50/II, 8010 Graz, Austria.
Thomas O EichmannInstitute of Molecular Biosciences, University of Graz, Humboldtstraße 50/II, 8010 Graz, Austria.
Sepp D KohlweinInstitute of Molecular Biosciences, University of Graz, Humboldtstraße 50/II, 8010 Graz, Austria.
Gerald N RechbergerInstitute of Molecular Biosciences, University of Graz, Humboldtstraße 50/II, 8010 Graz, Austria; Omics Center Graz, Austria. Electronic address: gerald.rechberger@uni-graz.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new UPLC-based untargeted lipidomic approach using a qTOF hybrid mass spectrometer is introduced. The applied binary gradient enables separations of lipid species including constitutional isomeric compounds and low abundant lipid classes such as phosphatidic acid (PA). Addition of phosphoric acid to the solvents improves peak shapes for acidic phospholipids. MS(E) scans allow simultaneous acquisition of full scan data and collision induced fragmentation to improve identification of lipid classes and to obtain structural information. The method was used to investigate the lipidome of yeast.

Indexed as

AnimalsChromatography, High Pressure LiquidGlycerophospholipidsLipidsMass SpectrometryMiceMusclesPhosphoric AcidsYeastsGlycerophospholipidsLipidsphosphoric acidPhosphoric AcidsGlycerophospholipidsLipidomicsMass spectrometryNeutral lipidsUltra-performance liquid chromatography

Identifiers

PMID24548922
PMCPMC3946075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.