Evidence map›Paper›PMID 24548561›Full record

ReviewFEBS letters2014

The Angiomotins--from discovery to function.

Susana Moleirinho, William Guerrant, Joseph L Kissil

Abstract readReview
In one paragraph

Review in FEBS letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 115 citations in OpenAlex.

  1. Article
  2. Identification of PKN2 and MOB4 as Coordinators of Collective Cell Migration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Identification of AMOTL2 as an antiviral factor that enhances the human type I interferon response against Zika virus.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Cancers · 2022
    Review
  17. Multivalent Angiomotin-like 1 and Yes-associated protein form a dynamic complex.Protein science : a publication of the Protein Society · 2022
    Article
  18. Article
  19. Review
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Susana MoleirinhoDepartment of Cancer Biology, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA.
William GuerrantDepartment of Cancer Biology, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA.
Joseph L KissilDepartment of Cancer Biology, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA. Electronic address: jkissil@scripps.edu.
Scripps Research Institute · US

Funding

The Role of RAC1 in CancerR01CA124495 · NCI · WISTAR INSTITUTE · PI KISSIL, JOSEPH · 2009 to 2018
$3.9M
Mechanisms of cell contact inhibition and their dysregulation in cancer.R01NS077952 · NINDS · SCRIPPS FLORIDA · PI KISSIL, JOSEPH · 2013 to 2017
$2.1M
NCI NIH HHS R01 CA124495NINDS NIH HHS R01 NS077952
6 · The paper itself

Abstract

Angiomotins were originally identified as angiostatin binding proteins and implicated in the regulation of endothelial cell migration. Recent studies have shed light on the role of Angiomotins and other members of the Motin protein family in epithelial cells and in pathways directly linked to the pathogenesis of cancer. In particular, Motins have been shown to play a role in signaling pathways regulated by small G-proteins and the Hippo-YAP pathway. In this review the role of the Motin protein family in these signaling pathways will be described and open questions will be discussed.

Indexed as

AngiomotinsAnimalsDiseaseEndothelial CellsGene Expression RegulationHumansIntercellular Signaling Peptides and ProteinsMembrane ProteinsMicrofilament ProteinsNeovascularization, PhysiologicSignal TransductionAMOT protein, humanAngiomotinsIntercellular Signaling Peptides and ProteinsMembrane ProteinsMicrofilament ProteinsAngiomotinAngiomotin-like 1Angiomotin-like 2HippoMerlinMotinNF2YAP

Identifiers

PMID24548561
PMCPMC4112001
OpenAlexW2038411007

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.