ArticleBrain sciences2013
Development of Brain EEG Connectivity across Early Childhood: Does Sleep Play a Role?
Article in Brain sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- The association between infant sleep, cognitive, and psychomotor development: a systematic review.Sleep · 2024Pooled it
- Early Life Sleep Deprivation and Brain Development: Insights From Human and Animal Studies.Frontiers in neuroscience · 2022Pooled it
- A Mixed Lipid Emulsion Containing Fish Oil and Its Effect on Electrophysiological Brain Maturation in Infants of Extremely Low Birth Weight: A Secondary Analysis of a Randomized Clinical Trial.The Journal of pediatrics · 2019Trial
- Development of nap neurophysiology: preliminary insights into sleep regulation in early childhood.Journal of sleep research · 2016Trial
- Tracing infant sleep neurophysiology longitudinally from 3 to 6 months: EEG insights into brain development.Npj biological timing and sleep · 2026Article
- Infant sleep EEG features at 4 months as biomarkers of neurodevelopment at 18 months.Pediatric research · 2025Article
- Disruption of functional network development in children with prenatal Zika virus exposure revealed by resting-state EEG.Scientific reports · 2025Article
- Article
- The sleeping brain's connectivity and family environment: characterizing sleep EEG coherence in an infant cohort.Scientific reports · 2023Article
- The Associations between 24-Hour Movement Behaviours and Quality of Life in Preschoolers: A Compositional Analysis of Cross-Sectional Data from 2018-2021.International journal of environmental research and public health · 2022Article
- Relations between sleep patterns early in life and brain development: A review.Developmental cognitive neuroscience · 2022Review
- Networks of cortical activity in infants with epilepsy.Brain communications · 2022Article
- Sleep and human cognitive development.Sleep medicine reviews · 2021Review
- Mismatched response predicts behavioral speech discrimination outcomes in infants with hearing loss and normal hearing.Infancy : the official journal of the International Society on Infant Studies · 2021Article
- The Maximum Eigenvalue of the Brain Functional Network Adjacency Matrix: Meaning and Application in Mental Fatigue Evaluation.Brain sciences · 2020Article
- Article
- Mental Sleep Activity and Disturbing Dreams in the Lifespan.International journal of environmental research and public health · 2019Review
- Functional brain connectivity in a rodent seizure model of autistic-like behavior.Epilepsy & behavior : E&B · 2019Article
- Maturation changes the excitability and effective connectivity of the frontal lobe: A developmental TMS-EEG study.Human brain mapping · 2019Article
- Early Life Sleep Deprivation: Role of Oxido-Inflammatory Processes.Neuroscience · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Sleep has beneficial effects on brain function and learning, which are reflected in plastic changes in the cortex. Early childhood is a time of rapid maturation in fundamental skills-e.g., language, cognitive control, working memory-that are predictive of future functioning. Little is currently known about the interactions between sleep and brain maturation during this developmental period. We propose coherent electroencephalogram (EEG) activity during sleep may provide unique insight into maturational processes of functional brain connectivity. Longitudinal sleep EEG assessments were performed in eight healthy subjects at ages 2, 3 and 5 years. Sleep EEG coherence increased across development in a region- and frequency-specific manner. Moreover, although connectivity primarily decreased intra-hemispherically across a night of sleep, an inter-hemispheric overnight increase occurred in the frequency range of slow waves (0.8-2 Hz), theta (4.8-7.8 Hz) and sleep spindles (10-14 Hz), with connectivity changes of up to 20% across a night of sleep. These findings indicate sleep EEG coherence reflects processes of brain maturation-i.e., programmed unfolding of neuronal networks-and moreover, sleep-related alterations of brain connectivity during the sensitive maturational window of early childhood.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.