ReviewCurrent opinion in pediatrics2014
Neuroimaging is a novel tool to understand the impact of environmental chemicals on neurodevelopment.
Review in Current opinion in pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 28 citations in OpenAlex.
- Environmental Exposures and Neuroimaging in Children with Neurodevelopmental Disorders: A Scoping Review.Current environmental health reports · 2026Article
- Fetal and postnatal metal metabolism-related changes in brain function are associated with childhood behavioral deficits.Science advances · 2026Article
- Early-Life Critical Windows of Susceptibility to Manganese Exposure and Sex-Specific Changes in Brain Connectivity in Late Adolescence.Biological psychiatry global open science · 2023Article
- Topological network properties of resting-state functional connectivity patterns are associated with metal mixture exposure in adolescents.Frontiers in neuroscience · 2023Article
- Pesticide exposure and cortical brain activation among farmworkers in Costa Rica.Neurotoxicology · 2022Article
- Associations of Air Pollution on the Brain in Children: A Brain Imaging Study.Research report (Health Effects Institute) · 2022Article
- Prenatal PMNeurotoxicology · 2020Article
- The personality dispositions and resting-state neural correlates associated with aggressive children.Social cognitive and affective neuroscience · 2020Article
- Imaging methods used in the assessment of environmental disease networks: a brief review for clinicians.Insights into imaging · 2020Review
- A preliminary study on prenatal polybrominated diphenyl ether serum concentrations and intrinsic functional network organization and executive functioning in childhood.Journal of child psychology and psychiatry, and allied disciplines · 2019Article
- Neurotoxicity of pesticides.Acta neuropathologica · 2019Review
- Neurotoxicity of polychlorinated biphenyls and related organohalogens.Acta neuropathologica · 2019Review
- Manganese exposure and working memory-related brain activity in smallholder farmworkers in Costa Rica: Results from a pilot study.Environmental research · 2019Article
- Prenatal exposures and infant brain: Review of magnetic resonance imaging studies and a population description analysis.Human brain mapping · 2019Review
- Early-life dentine manganese concentrations and intrinsic functional brain connectivity in adolescents: A pilot study.PloS one · 2019Article
- The Brain before Birth: Using fMRI to Explore the Secrets of Fetal Neurodevelopment.Environmental health perspectives · 2018Article
- The Effects of Air Pollution on the Brain: a Review of Studies Interfacing Environmental Epidemiology and Neuroimaging.Current environmental health reports · 2018Review
- Prenatal manganese exposure and intrinsic functional connectivity of emotional brain areas in children.Neurotoxicology · 2018Article
- Brain Development in Fetuses of Mothers with Diabetes: A Case-Control MR Imaging Study.AJNR. American journal of neuroradiology · 2017Article
- Research Review: Environmental exposures, neurodevelopment, and child mental health - new paradigms for the study of brain and behavioral effects.Journal of child psychology and psychiatry, and allied disciplines · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewThe prevalence of childhood neurodevelopmental disorders has been increasing over the last several decades. Prenatal and early childhood exposure to environmental toxicants is increasingly recognized as contributing to the growing rate of neurodevelopmental disorders. Very little information is known about the mechanistic processes by which environmental chemicals alter brain development. We review the recent advances in brain imaging modalities and discuss their application in epidemiologic studies of prenatal and early childhood exposure to environmental toxicants. RECENT
findingsNeuroimaging techniques (volumetric and functional MRI, diffusor tensor imaging, and magnetic resonance spectroscopy) have opened unprecedented access to study the developing human brain. These techniques are noninvasive and free of ionization radiation making them suitable for research applications in children. Using these techniques, we now understand much about structural and functional patterns in the typically developing brain. This knowledge allows us to investigate how prenatal exposure to environmental toxicants may alter the typical developmental trajectory. SUMMARY: MRI is a powerful tool that allows in-vivo visualization of brain structure and function. Used in epidemiologic studies of environmental exposure, it offers the promise to causally link exposure with behavioral and cognitive manifestations and ultimately to inform programs to reduce exposure and mitigate adverse effects of exposure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.