ReviewNature reviews. Neurology2014
Altered processing of sensory stimuli in patients with migraine.
Review in Nature reviews. Neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06882122 (Neurophysiological and Biomolecular Effects of Atogepant in High Frequency Episodic Migraine), which is not on this map. Cited by 164 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neurophysiological and Biomolecular Effects of Atogepant in High Frequency Episodic Migraine (ATOM Project)
Who cites it
164 citing papers in PubMed, 5 syntheses or guidelines pooled it, 336 citations in OpenAlex.
- The Effectiveness of Vestibular Rehabilitation in Vestibular Migraine: A Systematic Review.Journal of the Association for Research in Otolaryngology : JARO · 2026Pooled it
- Sleep macro- and microstructure in migraine and cluster headache: a systematic review of objective assessments.The journal of headache and pain · 2026Pooled it
- Visual Processing During the Interictal Period Between Migraines: A Meta-Analysis.Neuropsychology review · 2023Pooled it
- Which is the best transcranial direct current stimulation protocol for migraine prevention? A systematic review and critical appraisal of randomized controlled trials.The journal of headache and pain · 2021Pooled it
- Differential efficacy of non-invasive vagus nerve stimulation for the acute treatment of episodic and chronic cluster headache: A meta-analysis.Cephalalgia : an international journal of headache · 2019Pooled it
- Efficacy of a dual task protocol on neurophysiological and clinical outcomes in migraine: a randomized control trial.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Trial
- Occipital transcranial direct current stimulation in episodic migraine patients: effect on cerebral perfusion.Scientific reports · 2023Trial
- Duration and frequency of migraines affect cognitive function: evidence from neuropsychological tests and event-related potentials.The journal of headache and pain · 2017Trial
- Effects of OnabotulintoxinA on Habituation of Laser Evoked Responses in Chronic Migraine.Toxins · 2016Trial
- Salience Network Dynamics Across Spontaneous Attacks, Interictal Rest and Interictal Pain Imagery in Menstrually Related Migraine.Brain topography · 2026Article
- Semantic Content of Visual Consequent Stimuli Modulates Audiovisual Learning in Migraine.Brain and behavior · 2026Article
- Migraine and auditory dysfunction: beyond comorbidity.Journal of neurology · 2026Review
- Oscillatory edge connectivity in pain-related regions supports machine learning identification of migraine.The journal of headache and pain · 2026Article
- Clinical characteristics of pure menstrual migraine and menstrually-related migraine: a cross-sectional online questionnaire study.BMC neurology · 2026Article
- Kinematic analysis of multisensory integration and sensory load induced fatigue in migraine.Scientific reports · 2026Article
- Self-compassion in migraine: associations with depression, anxiety, and clinical characteristics.Arquivos de neuro-psiquiatria · 2026Article
- Article
- Identification of Copy Number Variations in Familial Hemiplegic Migraine Genes in Suspected Hemiplegic Migraine Patients.Biomedicines · 2026Article
- Clinical utility and prospective of TMS-EEG: Updated review from an international expert group.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Review
- Changes in brainstem habituation during onabotulinumtoxinA treatment in chronic migraine: A prospective case-control study.Headache · 2026Article
104 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Migraine is a cyclic disorder, in which functional and morphological brain changes fluctuate over time, culminating periodically in an attack. In the migrainous brain, temporal processing of external stimuli and sequential recruitment of neuronal networks are often dysfunctional. These changes reflect complex CNS dysfunction patterns. Assessment of multimodal evoked potentials and nociceptive reflex responses can reveal altered patterns of the brain's electrophysiological activity, thereby aiding our understanding of the pathophysiology of migraine. In this Review, we summarize the most important findings on temporal processing of evoked and reflex responses in migraine. Considering these data, we propose that thalamocortical dysrhythmia may be responsible for the altered synchronicity in migraine. To test this hypothesis in future research, electrophysiological recordings should be combined with neuroimaging studies so that the temporal patterns of sensory processing in patients with migraine can be correlated with the accompanying anatomical and functional changes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.