ArticleThe Journal of cell biology1988
Tyrosine phosphorylated proteins in different tissues during chick embryo development.
Article in The Journal of cell biology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 83 citations in OpenAlex.
- Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation.Physiological reviews · 2011Review
- Protein phosphorylation during coconut zygotic embryo developmentPlant physiology · 1998Article
- A novel role for vitamin K1 in a tyrosine phosphorylation cascade during chick embryogenesis.The Journal of clinical investigation · 1997Article
- Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes.Molecular and cellular biology · 1994Article
- Activation of phosphotyrosine phosphatase activity by reduction of cell-substrate adhesion.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene.The Journal of cell biology · 1993Article
- A role of tyrosine phosphorylation in the formation of acetylcholine receptor clusters induced by electric fields in cultured Xenopus muscle cells.The Journal of cell biology · 1993Article
- Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts.The Journal of cell biology · 1992Article
- The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions.The EMBO journal · 1992Article
- Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein.Cell regulation · 1991Article
- Paxillin is a major phosphotyrosine-containing protein during embryonic development.The Journal of cell biology · 1991Article
- Identification of chicken embryo kinase 5, a developmentally regulated receptor-type tyrosine kinase of the Eph family.Cell regulation · 1991Article
- Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated.The Journal of cell biology · 1991Article
- Membrane-anchored form of v-sis/PDGF-B induces mitogenesis without detectable PDGF receptor autophosphorylation.The Journal of cell biology · 1991Article
- Tissue-dependent regulation of protein tyrosine kinase activity during embryonic development.The Journal of cell biology · 1991Article
- Modulation of intercellular adherens-type junctions and tyrosine phosphorylation of their components in RSV-transformed cultured chick lens cells.Cell regulation · 1991Article
- Paxillin: a new vinculin-binding protein present in focal adhesions.The Journal of cell biology · 1990Article
- A distinctive family of embryonic protein-tyrosine kinase receptors.Proceedings of the National Academy of Sciences of the United States of America · 1990Article
- Intestinal crypt stem cells possess high levels of cytoskeletal-associated phosphotyrosine-containing proteins and tyrosine kinase activity relative to differentiated enterocytes.The Journal of cell biology · 1989Article
- Identification of a developmentally regulated protein-tyrosine kinase by using anti-phosphotyrosine antibodies to screen a cDNA expression library.Proceedings of the National Academy of Sciences of the United States of America · 1989Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A high affinity polyclonal antibody specific for phosphotyrosyl residues has been used in immunoblotting experiments to survey developing embryonic chicken tissues for the presence and characteristics of tyrosine phosphorylated proteins. Proteins phosphorylated on tyrosine were found to be present in all the embryonic tissues examined, including heart, thigh, gizzard, intestine, lung, liver, kidney, brain, and lens, from 7 to 21 d of development in ovo, but were greatly reduced or absent in the same tissues taken from adult chickens. A limited number of major tyrosine phosphorylated proteins were seen in all the tissues examined and they ranged in molecular mass from 35 to 220 kD. Most of the tissues contained proteins phosphorylated on tyrosine with apparent molecular masses of 120, 70, 60, and 35 kD, suggesting that the substrates of tyrosine protein kinases in different tissues may be related proteins. One-dimensional peptide mapping of the 120- and 70-kD protein bands indicated a close structural relationship among the phosphotyrosine-containing proteins of 120 kD, and similarly among those of 70 kD, from the different tissues.
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