ArticleThe American journal of tropical medicine and hygiene2014
Infection of laboratory-colonized Anopheles darlingi mosquitoes by Plasmodium vivax.
Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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Who cites it
44 citing papers in PubMed, 67 citations in OpenAlex.
- Metabolic reprogramming and gut microbiota ecology drive divergent Plasmodium vivax infection outcomes in Anopheles darlingi.PLoS pathogens · 2025Article
- From Colonization to High Production andBio-protocol · 2025Article
- Article
- Two chromosomal reference genome sequences for the malaria mosquito,Wellcome open research · 2025Article
- Dietary para-aminobenzoic acid, uric acid, and antibiotics modulate the susceptibility ofFrontiers in cellular and infection microbiology · 2025Article
- Effects of Carbohydrate Intake onInsects · 2024Article
- Case Report: Plasmodium vivax Sporozoite Melanization in the Midgut and Salivary Gland of the Malaria Vector Anopheles darlingi.The American journal of tropical medicine and hygiene · 2024Article
- Evaluation of insemination, blood feeding, and Plasmodium vivax infection effects on locomotor activity patterns of the malaria vector Anopheles darlingi (Diptera: Culicidae).Parasitology research · 2023Article
- Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi.Scientific reports · 2023Article
- Detection of Plasmodium simium gametocytes in non-human primates from the Brazilian Atlantic Forest.Malaria journal · 2023Article
- Bacterial Microbiota from Lab-Reared and Field-CapturedMicroorganisms · 2023Article
- Transmission efficiency of Plasmodium vivax at low parasitaemia.Malaria journal · 2023Article
- Malaria Resilience in South America: Epidemiology, Vector Biology, and Immunology Insights from the Amazonian International Center of Excellence in Malaria Research Network in Peru and Brazil.The American journal of tropical medicine and hygiene · 2022Article
- Relative contribution of low-density and asymptomatic infections toLancet regional health. Americas · 2022Article
- Assessment of antibiotic treatment onFrontiers in microbiology · 2022Article
- Optimization of Plasmodium vivax sporozoite production from Anopheles stephensi in South West India.Malaria journal · 2021Article
- Flight tone characterisation of the South American malaria vector Anopheles darlingi (Diptera: Culicidae).Memorias do Instituto Oswaldo Cruz · 2021Article
- Vector-Focused Approaches to Curb Malaria Transmission in the Brazilian Amazon: An Overview of Current and Future Challenges and Strategies.Tropical medicine and infectious disease · 2020Review
- Comparison of infectivity of Plasmodium vivax to wild-caught and laboratory-adapted (colonized) Anopheles arabiensis mosquitoes in Ethiopia.Parasites & vectors · 2020Article
- Evidence for family-level variation of phenotypic traits in response to temperature of Brazilian Nyssorhynchus darlingi.Parasites & vectors · 2020Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
Anopheles darlingi Root is the most important malaria vector in the Amazonia region of South America. However, continuous propagation of An. darlingi in the laboratory has been elusive, limiting entomological, genetic/genomic, and vector-pathogen interaction studies of this mosquito species. Here, we report the establishment of an An. darlingi colony derived from wild-caught mosquitoes obtained in the northeastern Peruvian Amazon region of Iquitos in the Loreto Department. We show that the numbers of eggs, larvae, pupae, and adults continue to rise at least to the F6 generation. Comparison of feeding Plasmodium vivax ex vivo of F4 and F5 to F1 generation mosquitoes showed the comparable presence of oocysts and sporozoites, with numbers that corresponded to blood-stage asexual parasitemia and gametocytemia, confirming P. vivax vectorial capacity in the colonized mosquitoes. These results provide new avenues for research on An. darlingi biology and study of An. darlingi-Plasmodium interactions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.