ReviewCurrent opinion in chemical biology2014
Recent discoveries and applications involving small-molecule microarrays.
Review in Current opinion in chemical biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Machine Learning Informs RNA-Binding Chemical Space.Angewandte Chemie (International ed. in English) · 2023Article
- Designing strategies of small-molecule compounds for modulating non-coding RNAs in cancer therapy.Journal of hematology & oncology · 2022Review
- Three-Color Imaging Enables Simultaneous Screening of Multiple RNA Targets on Small Molecule Microarrays.Current protocols in chemical biology · 2020Article
- Discovery of a Potent GLUT Inhibitor from a Library of Rapafucins by Using 3D Microarrays.Angewandte Chemie (International ed. in English) · 2019Article
- Molecular Characterization of Mucus Binding.Biomacromolecules · 2019Article
- Probing theMedChemComm · 2018Article
- Article
- Identification and correction of spatial bias are essential for obtaining quality data in high-throughput screening technologies.Scientific reports · 2017Article
- Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays.ACS chemical biology · 2017Article
- The Emerging Role of RNA as a Therapeutic Target for Small Molecules.Cell chemical biology · 2016Review
- Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival.Scientific reports · 2016Article
- Developing an Efficient and General Strategy for Immobilization of Small Molecules onto Microarrays Using Isocyanate Chemistry.Sensors (Basel, Switzerland) · 2016Article
- Advances in discovering small molecules to probe protein function in a systems context.Current opinion in chemical biology · 2016Review
- Quantitative dose-response curves from subcellular lipid multilayer microarrays.Lab on a chip · 2015Article
- Probing small-molecule microarrays with tagged proteins in cell lysates.Current protocols in chemical biology · 2014Article
- Assemblages: functional units formed by cellular phase separation.The Journal of cell biology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
High-throughput and unbiased binding assays have proven useful in probe discovery for a myriad of biomolecules, including targets of unknown structure or function and historically challenging target classes. Over the past decade, a number of novel formats for executing large-scale binding assays have been developed and used successfully in probe discovery campaigns. Here we review the use of one such format, the small-molecule microarray (SMM), as a tool for discovering protein-small molecule interactions. This review will briefly highlight selected recent probe discoveries using SMMs as well as novel uses of SMMs in profiling applications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.