ReviewIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2014
Pathophysiology and treatment of tinnitus: an elusive disease.
Review in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07071480 (Noninvasive Therapeutic Hypothermia for Tinnitus), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Noninvasive Therapeutic Hypothermia for Tinnitus
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Temporomandibular joint disorders and tinnitus: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Repurposing Renin-Angiotensin System Drugs for the Treatment of Audiovestibular Disorders.Journal of clinical medicine · 2026Review
- Effect of oral caroverine in the treatment of tinnitus: A quasi-experimental study.Journal of family medicine and primary care · 2024Article
- Tinnitus Prevalence, Associated Characteristics, and Treatment Patterns among Adults in Saudi Arabia.Audiology research · 2024Article
- Artificial intelligence approaches for tinnitus diagnosis: leveraging high-frequency audiometry data for enhanced clinical predictions.Frontiers in artificial intelligence · 2024Article
- A proposed association between subjective nonpulsatile tinnitus and migraine.World journal of otorhinolaryngology - head and neck surgery · 2023Review
- Cranial nerve palsy prevalence and associated factors in patients with malignant otitis externa.Laryngoscope investigative otolaryngology · 2023Article
- Relationship Between Serum Levels of Brain-Derived Neurotrophic Factor (BDNF) and Hearing Loss and Tinnitus.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- A Study to Grade the Severity of Tinnitus and its Psychological Impact Using Tinnitus Functional Index (tfi).Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- Tinnitus: systematic approach to primary care assessment and management.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022Article
- The frequency of dyslipidemia in patients with idiopathic tinnitus.Northern clinics of Istanbul · 2022Article
- The genetic architecture of age-related hearing impairment revealed by genome-wide association analysis.Communications biology · 2021Article
- A Systematic Review and Meta-analysis of Randomized Controlled Trials on the Effect of Transcranial Magnetic Stimulation on Tinnitus Management.Central Asian journal of global health · 2020Review
- Tinnitus and Cognition: Linked?Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019Article
- Radiological Evaluation of Inner Ear with Computed Tomography in Patients with Unilateral Non-Pulsatile Tinnitus.The journal of international advanced otology · 2018Article
- Prolonged noise exposure-induced auditory threshold shifts in rats.Hearing research · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tinnitus is a perception of sound in proximity to the head with the absence of an external source. It is estimated to occur in 15-20% of the world's population, with 1-3% of cases severely affecting quality of life. Severe tinnitus is frequently associated with depression, anxiety and insomnia. Tinnitus has been associated with a variety of risk factors, including prolonged noise exposure, head and neck injury and infection. The most recent pathophysiologic theory of tinnitus suggests that the central nervous system is the source or "generator" of this condition. However, treatment modalities are still aimed at lessening the awareness of tinnitus and its impact on quality of life rather than attaining a definitive cure. Currently, no drug is available that has demonstrated replicable, long-term reduction of tinnitus impact in excess of placebo effects. However, the market value of such an agent is estimated to be $1.1 billion, with a potential for increase with an aging and longer-living population. This review assesses the current developments in the pathophysiology and treatment for tinnitus, which remains a chronic and debilitating condition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.