Evidence map›Paper›PMID 24533159›Full record

ArticlePloS one2014

Waist to height ratio is an independent predictor for the incidence of chronic kidney disease.

Keiichi Odagiri, Isagi Mizuta, Makoto Yamamoto, Yosuke Miyazaki, Hiroshi Watanabe, Akihiko Uehara

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

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  11. Waist height ratio predicts chronic kidney disease: a systematic review and meta-analysis, 1998-2019.Archives of public health = Archives belges de sante publique · 2019
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  16. The kidney in obesity.Current hypertension reports · 2015
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Keiichi OdagiriDepartment of Clinical Pharmacology and Therapeutics, Hamamatsu University School of Medicine, Higashi-ku, Hamamatsu, Japan.
Isagi MizutaYamaha Health Care Center, Naka-ku, Hamamatsu, Japan.
Makoto YamamotoYamaha Health Care Center, Naka-ku, Hamamatsu, Japan.
Yosuke MiyazakiDepartment of Mental Health, Institute of Industrial Ecological Sciences, School of Medicine, University of Occupational and Environmental Health, Yahatanishi-ku, Kitakyushu, Japan.
Hiroshi WatanabeDepartment of Clinical Pharmacology and Therapeutics, Hamamatsu University School of Medicine, Higashi-ku, Hamamatsu, Japan.
Akihiko UeharaYamaha Health Care Center, Naka-ku, Hamamatsu, Japan.
Yamaha (Japan) · JPHamamatsu University School of Medicine · JPUniversity of Occupational and Environmental Health Japan · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveObesity is a risk factor for chronic kidney disease (CKD) and cardiovascular disease. The association between waist to height ratio (WheiR) and CKD is unclear. This study evaluated the association between WheiR and CKD. DESIGN AND

methodsIn this longitudinal cohort study, 4841 Japanese workers (3686 males, 1155 females) 18 to 67 years of age in 2008 were followed up until 2011. CKD was defined as an estimated glomerular filtration rate of <60 mL/min/1.73 m² (by the Modification of Diet in Renal Disease equation for Japanese) or dipstick proteinuria (≥1+). Cox proportional hazards models were used to examine the relationship between WheiR and development of CKD.

resultsA total of 384 (7.9%) participants (300 men and 84 women) were found to have new CKD. The incidence of CKD was 13.7, 24.2, 37.9 and 43.7 per 1000 person-years of follow-up in the lowest, second, third and highest quartiles of WheiR, respectively. After adjustment for potential confounders, the adjusted hazard ratios (95% confidence interval) for CKD were 1.00 (reference), 1.23 (0.85, 1.78), 1.59 (1.11, 2.26) and 1.62 (1.13, 2.32) through the quartiles of WheiR, respectively. WheiR had a significant predictive value for the incidence of both proteinuria and low estimated glomerular filtration rate. After subdivision according to gender, the relationship between WheiR and the incidence of CKD was statistically significant in the unadjusted model. However, after adjusting for potential confounders, WheiR was significantly associated with the incidence of CKD in females, whereas it was not significant in males.

conclusionsWheiR, which is commonly used as an index of central obesity, is associated with CKD. There was a significant gender difference in the relationship between CKD and WheiR.

Indexed as

Waist-Height RatioAdolescentAdultAgedBiomarkersCohort StudiesFemaleGlomerular Filtration RateHumansIncidenceJapanLongitudinal StudiesMaleMiddle AgedObesityProteinuriaBiomarkers

Identifiers

PMID24533159
PMCPMC3923056
OpenAlexW2055645343

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.