Evidence map›Paper›PMID 24532970›Full record

ArticleTherapeutics and clinical risk management2014

Clinical differences between H3N2 and H1N1 influenza 2012 and lower respiratory tract infection found using a statistical classification approach.

Dimitris Petridis, Paul Zarogoulidis, Anastasios Kallianos, Ioannis Kioumis, Georgia Trakada, Dionysios Spyratos, Antonis Papaiwannou, Konstantinos Porpodis, Haidong Huang, Aggeliki Rapti and 2 more

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Severity of Clinical Presentation and Outcomes in Hospitalized Adult People With Influenza by Type and Subtype, United States-2017-2020.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 3 countries.

Dimitris PetridisDepartment of Food Technology, Alexander Technological Educational Institute of Thessaloniki, Thessaloniki, Greece.
Paul ZarogoulidisPulmonary Department, "G Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; Department of Interventional Pneumology, Ruhrlandklinik, West German Lung Center, University Hospital, University Duisburg-Essen, Essen, Germany.
Anastasios Kallianos2nd Pulmonary Department, "Sotiria" Hospital for Chest Diseases, Athens, Greece.
Ioannis KioumisPulmonary Department, "G Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Georgia TrakadaDepartment of Clinical Therapeutics, Division of Pneumonology, Medical School, National University of Athens, Athens, Greece.
Dionysios SpyratosPulmonary Department, "G Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Antonis PapaiwannouPulmonary Department, "G Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Konstantinos PorpodisPulmonary Department, "G Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Haidong HuangDepartment of Respiratory Diseases, Changhai Hospital/First Affiliated Hospital of the Second Military Medical University, Shanghai, People's Republic of China.
Aggeliki Rapti2nd Pulmonary Department, "Sotiria" Hospital for Chest Diseases, Athens, Greece.
Wolfgang Hohenforst-SchmidtII Medical Department, "Coburg" Regional Clinic, University of Wüerzburg, Coburg, Germany.
Konstantinos ZarogoulidisPulmonary Department, "G Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
G. Papanikolaou General Hospital · GRSotiria General Hospital · GRAlexander Technological Educational Institute of Thessaloniki · GRAristotle University of Thessaloniki · GRKlinikum Coburg · DENational and Kapodistrian University of Athens · GRRuhrlandklinik · DESecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfluenza A H1N1 and H3N2 are two influenza waves that have been identified in past years.

methodsData from 77 inpatients from three tertiary hospitals were included and statistical analysis was performed in three different clusters.

resultsThirty-four patients (44.2%) had respiratory distress upon admission, 31.2% had a smoking history or were active smokers, 37.7% manifested disease symptoms, and 7.8% were obese (body mass index >41). The mean age of patients was 51.1 years. Cough was the most common symptom observed in 77.9% of the patients, accompanied by sputum production (51.9%) and fatigue (42.9%). Hemoptysis and vomiting were rarely recorded in the patients (9.1% and 16.9%, respectively). Oseltamivir administration varied between 0 and 10 days, giving a mean value of 2.2 days. In particular, 19 patients received no drug, 31 patients received drug for only for 1 day, 19 patients for 5 days, and 8 patients from 2 to 10 days.

conclusionClusters of symptoms can be used to identify different types of influenza and disease severity. Patients with vaccination had pneumonia, whereas patients without vaccination had influenza A. Patients more than 54.5 years old had H3N2 and patients less than 54.5 years had H1N1. White blood cell count values increased from normal to elevated in H3N2 patients but still remained abnormal in lower tract infection and H1N1 patients.

Indexed as

H1N1H3N2influenza outbreakrespiratory infectionvaccination

Identifiers

PMID24532970
PMCPMC3923611
OpenAlexW2057832447

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.