Evidence map›Paper›PMID 24532898›Full record

ArticleMedical journal, Armed Forces India2012

Comparison of PET/CT with conventional imaging modalities (USG, CECT) in evaluation of N0 neck in head and neck squamous cell carcinoma.

Ashutosh Chauhan, Pranjal Kulshrestha, Sanjay Kapoor, Harkirat Singh, M J Jacob, Maneel Patel, Manomoy Ganguly

Open access · greenAbstract read
In one paragraph

Article in Medical journal, Armed Forces India, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Multicenter Trial of [Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019
    Trial
  2. Review
  3. Article
  4. Review
  5. Review
  6. FDG-PET/CT and Pathology in Newly Diagnosed Head and Neck Cancer: ACRIN 6685 Trial, FDG-PET/CT cN0.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ashutosh ChauhanClassified Specialist (Surgery & Oncosurgeon), Command Hospital (CC), Lucknow, India.
Pranjal KulshresthaResident, Oncology Center, AH (R&R), New Delhi, India.
Sanjay KapoorConsultant (Surgery & Oncosurgery), Command Hospital (CC), Lucknow, India.
Harkirat SinghSenior Advisor (Nuclear Medicine), Command Hospital (SC), Pune 411040, India.
M J JacobSenior Advisor (Nuclear Medicine), INHS Asvini, Colaba, Mumbai, India.
Maneel PatelClassified Specialist (Radiodiagnosis), INHS Dhanvantari, Port Blair, India.
Manomoy GangulyCommandant, Military Hospital, Roorkee, India.
Command Hospital · ININHS Asvini · INIndian Institute of Technology Roorkee · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvaluation of a clinically N0 neck is mandatory in cases of squamous cell carcinoma of head and neck region in order to determine the need to address the neck. The study was designed to compare the accuracy of PET/CT scan with that of USG and CECT Neck in assessing clinically N0 neck in cases of squamous cell carcinoma of upper aerodigestive tract.

methodsSingle center, prospective, study over a 2 year period. All Cases of squamous cell carcinoma of upper aerodigestive tract with no palpable neck lymphadenopathy and who were scheduled for surgery were evaluated with USG, CECT and 18F-FDG PET/CT, of the neck. Post operative histopathology was correlated with pre-operative nodal status. Statistical analysis was done using the chi square test.

resultsIn the 49 patients enrolled, 51 neck sides underwent dissections. Sensitivity of USG, CECT and PET-CT was 4.76%, 23.80% and 71.43% respectively while the specificity was 93.33%, 93.33% and 96.67% respectively. The positive predictive value (PPV) calculated for USG, CECT and PET-CT was 33.33%, 71%, 93.5% respectively while the negative predictive value (NPV) 58.33%, 63.63% and 82.85% respectively.

conclusionsIn N0 neck in head and neck squamous cell carcinoma, though FDG-PET-CT is more accurate than either USG or CECT in staging of the neck, it is not accurate enough to alter the current treatment paradigm.

Indexed as

CECTN0 neck stagingPET/CTUltrasound

Identifiers

PMID24532898
PMCPMC3862837
OpenAlexW1976723131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.