Evidence map›Paper›PMID 24532323›Full record

ArticleAdvanced healthcare materials2014

Magnetic ligation method for quantitative detection of microRNAs.

Monty Liong, Hyungsoon Im, Maulik D Majmudar, Aaron D Aguirre, Matthew Sebas, Hakho Lee, Ralph Weissleder

Open access · greenAbstract read
In one paragraph

Article in Advanced healthcare materials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Monty LiongCenter for Systems Biology, Massachusetts General Hospital-Harvard Medical School, 185 Cambridge St., Boston, MA, 02114, USA.
Hyungsoon Im
Maulik D Majmudar
Aaron D Aguirre
Matthew Sebas
Hakho Lee
Ralph Weissleder
Center for Systems Biology · USHarvard University · USMassachusetts General Hospital · US

Funding

The role of microvesicles in giloma virotherapyP01CA069246 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CHAREST, ALAIN · 1996 to 2021
$30.9M
Shape Memory Polymer Devices for Treating StrokeR01EB000462 · NIBIB · UNIVERSITY OF CALIF-LAWRNC LVRMR NAT LAB · PI MAITLAND, DUNCAN J · 2002 to 2012
$12.5M
Training Grant in Molecular Imaging Research (MGH/HMS)T32CA079443 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2000 to 2025
$10.1M
Noninvasive Cardiovascular Imaging Research Training ProgramT32HL094301 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Marcelo F DI CARLI · 2010 to 2026
$7.8M
Magnetic nanoswitches for sensing biomoleculesR01EB004626 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2004 to 2012
$3.2M
Novel Clickdyes for Biomedical SensingR01EB010011 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2010 to 2017
$3.1M
MAGNETIC NANOSENSORS FOR BIOMEDICAL ANALYSES OF MICROVESICLESR01HL113156 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HAKHO · 2012 to 2016
$2.1M
Single Cell Imaging of the HeartR01HL122208 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2014 to 2017
$1.7M
NCI NIH HHS P01 CA069246NCI NIH HHS T32 CA079443NCI NIH HHS T32CA79443NHLBI NIH HHS HHSN268201000044CNHLBI NIH HHS R01 HL113156NHLBI NIH HHS R01-HL113156NHLBI NIH HHS R01 HL122208NHLBI NIH HHS T32 HL094301NIBIB NIH HHS R01 EB004626NIBIB NIH HHS R01-EB00462605A1NIBIB NIH HHS R01 EB010011NIBIB NIH HHS R01-EB010011
6 · The paper itself

Abstract

A magnetic ligation method is utilized for the detection of microRNAs among a complex biological background without polymerase chain reaction or nucleotide modification. The sandwich probes assay can be adapted to analyze a panel of microRNAs associated with cardiovascular diseases in heart tissue samples.

Indexed as

Molecular Probe TechniquesDNA LigasesMagnetite NanoparticlesMicroRNAsMicrospheresNucleic Acid Amplification TechniquesDNA LigasesMagnetite NanoparticlesMicroRNAsdiagnosticsenzymatic ligationmagnetic labelingmagnetic resonancemicroRNA

Identifiers

PMID24532323
PMCPMC4107040
OpenAlexW2073766926

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.