ArticleBMJ open2014
Influence of chronic exercise on carotid atherosclerosis in marathon runners.
Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Pooled it
- Acute effect of healthy walking on arterial stiffness in patients with type 2 diabetes and differences by age and sex: a pre-post intervention study.BMC cardiovascular disorders · 2019Trial
- Carotid atherosclerosis and aortic stiffness in masters athletes: Multimodality vascular phenotyping from the Master@Heart study.American journal of preventive cardiology · 2027Article
- Exercise-induced Hypertension and Carotid Intima-media Thickness in Male Marathon Runners.International journal of sports medicine · 2024Article
- A stacking ensemble model for predicting the occurrence of carotid atherosclerosis.Frontiers in endocrinology · 2024Article
- Serum and Urinary Neutrophil Gelatinase-Associated Lipocalin Are Not Associated With Serum Redox Parameters in Amateur Athletes After an Ultramarathon.Frontiers in physiology · 2022Article
- Exercise-Induced Regulation of Redox Status in Cardiovascular Diseases: The Role of Exercise Training and Detraining.Antioxidants (Basel, Switzerland) · 2019Review
- Sports engagement and age at first myocardial infarction in men under 55 years of age.PloS one · 2017Article
- Acute and Chronic Effects of Endurance Running on Inflammatory Markers: A Systematic Review.Frontiers in physiology · 2017Article
- Higher Daily Physical Activity Level Is Associated with Lower RBC Aggregation in Carotid Artery Disease Patients at High Risk of Stroke.Frontiers in physiology · 2017Article
- Bone Mineral Density Is Positively Related to Carotid Intima-Media Thickness: Findings From a Population-Based Study in Adolescents and Premenopausal Women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016Article
- Article
- Aortic augmentation index in endurance athletes: a role for cardiorespiratory fitness.European journal of applied physiology · 2016Article
- Regular physical activity and cardiovascular biomarkers in prevention of atherosclerosis in men: a 25-year prospective cohort study.BMC cardiovascular disorders · 2016Article
- Are There Deleterious Cardiac Effects of Acute and Chronic Endurance Exercise?Physiological reviews · 2016Review
- Effects of High-Intensity Training of Professional Runners on Myocardial Hypertrophy and Subclinical Atherosclerosis.PloS one · 2016Article
- Causes of changes in carotid intima-media thickness: a literature review.Cardiovascular ultrasound · 2015Review
- Cognitive Avoidant Coping Is Associated with Higher Carotid Intima Media Thickness Among Middle-Aged Adults.International journal of behavioral medicine · 2015Article
- Arterial stiffness is inversely associated with a better running record in a full course marathon race.Journal of exercise nutrition & biochemistry · 2014Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe effect of habitual, high-intensity exercise training on the progression of atherosclerosis is unclear. We assessed indices of vascular health (central systolic blood pressure (SBP) and arterial stiffness as well as carotid intima-medial thickness (cIMT)) in addition to cardiovascular risk factors of trained runners versus their untrained spouses or partners to evaluate the impact of exercise on the development of carotid atherosclerosis.
settingfield study at Boston Marathon.
participants42 qualifiers (mean age±SD: 46±13 years, 21 women) for the 2012 Boston Marathon and their sedentary domestic controls (46±12 years, n=21 women). OUTCOMES: We measured medical and running history, vital signs, anthropometrics, blood lipids, C reactive protein (CRP), 10 years Framingham risk, central arterial stiffness and SBP and cIMT.
resultsMultiple cardiovascular risk factors, including CRP, non-high-density lipoprotein cholesterol, triglycerides, heart rate, body weight and body mass index (all p<0.05), were reduced in the runners. The left and right cIMT, as well as central SBP, were not different between the two groups (all p>0.31) and were associated with age (all r≥0.41; p<0.01) and Framingham risk score (all r≥0.44; p<0.01) independent of exercise group (all p>0.08 for interactions). The amplification of the central pressure waveform (augmentation pressure at heart rate 75 bpm) was also not different between the two groups (p=0.07) but was related to age (p<0.01) and group (p=0.02) in a multiple linear regression model.
conclusionsHabitual endurance exercise improves the cardiovascular risk profile, but does not reduce the magnitude of carotid atherosclerosis associated with age and cardiovascular risk factors.
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Registered trials
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