Trial reportFertility and sterility2014
Effect of prior oophorectomy on changes in bone mineral density and carotid artery intima-media thickness in postmenopausal women.
Trial report in Fertility and sterility, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Opportunistic salpingectomy during radical cystectomy for bladder cancer: A systematic review of the literature.Asian journal of urology · 2025Review
- Habitual physical activity and sedentary behavior among women with and without premenopausal bilateral oophorectomy: an exploratory study.Menopause (New York, N.Y.) · 2025Article
- Steroid hormone levels and bone mineral density in women over 65 years of age.Scientific reports · 2023Article
- Osteoporosis management in hematologic stem cell transplant recipients: Executive summary.Journal of bone oncology · 2021Review
- Surgically Induced Menopause-A Practical Review of Literature.Medicina (Kaunas, Lithuania) · 2019Review
- Bone management in hematologic stem cell transplant recipients.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Review
- Ovarian Conservation and Overall Survival in Young Women With Early-Stage Cervical Cancer.Obstetrics and gynecology · 2017Article
- Hormone replacement therapy in young women with surgical primary ovarian insufficiency.Fertility and sterility · 2016Review
- Contributing factors for menopausal symptoms after surgical staging for endometrial cancer.Menopause (New York, N.Y.) · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo determine the effect of prior oophorectomy in healthy postmenopausal women on the rate of loss of bone mineral density (BMD) and rate of increase in carotid artery intima-media thickness (CIMT).
designSecondary analysis from a randomized controlled trial.
settingUniversity-based research clinic. PATIENT(S): Two hundred twenty-two healthy postmenopausal women in the Greater Los Angeles area. INTERVENTION(S): Baseline and annual screening of BMD and assessment of CIMT every 6 months for a total of 3 years. MAIN OUTCOME MEASURE(S): Changes in BMD and CIMT during postmenopausal years. RESULT(S): Among women who were menopausal for more than 10 years, the rate of CIMT progression was statistically significantly less in women with intact ovaries compared with those in women with prior oophorectomy. In women 5-10 years postmenopause, there was a trend toward a slower loss of BMD in those who retained their ovaries, and in women more than 10 years postmenopause there was significantly less BMD loss in those who retained their ovaries. CONCLUSION(S): As time from menopausal transition increases, retained ovaries are associated with a slower rate of bone loss and a slower rate of thickening of the carotid artery wall compared with rates in menopausal women with oophorectomy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.