Evidence map›Paper›PMID 24529517›Full record

ArticleAnnals of epidemiology2014

Do metropolitan HIV epidemic histories and programs for people who inject drugs and men who have sex with men predict AIDS incidence and mortality among heterosexuals?

Samuel R Friedman, Brooke S West, Barbara Tempalski, Cory M Morton, Charles M Cleland, Don C Des Jarlais, H Irene Hall, Hannah L F Cooper

Abstract read
In one paragraph

Article in Annals of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Samuel R FriedmanInstitute of Infectious Disease Research, National Development and Research Institutes, Inc., New York, NY; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. Electronic address: friedman@ndri.org.
Brooke S WestInstitute of Infectious Disease Research, National Development and Research Institutes, Inc., New York, NY.
Barbara TempalskiInstitute of Infectious Disease Research, National Development and Research Institutes, Inc., New York, NY.
Cory M MortonInstitute of Infectious Disease Research, National Development and Research Institutes, Inc., New York, NY.
Charles M ClelandCollege of Nursing, New York University, New York, NY.
Don C Des JarlaisBeth Israel Medical Center, New York, NY.
H Irene HallDivision of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
Hannah L F CooperBehavioral Sciences and Health Education, Rollins School of Public Health at Emory University, Atlanta, GA.
National Development and Research Institutes · USEmory University · USMount Sinai Beth Israel · USNational Center for HIV/AIDS Viral Hepatitis STD and TB Prevention · USNew York University · US

Funding

BEHAVIORAL SCI TRAINING IN DRUG ABUSE RESEARCHT32DA007233 · NIDA · PUBLIC HEALTH SOLUTIONS · PI GOLDSAMT, LLOYD A · 1985 to 2023
$20.2M
Risk Factors for HIV/AIDS in Drug UsersR01DA003574 · NIDA · NEW YORK UNIVERSITY · PI DES JARLAIS, DON C, MCKNIGHT, COURTNEY · 1986 to 2025
$16.2M
COMMUNITY VULNERABILITY AND RESPONSES TO IDU-RELATED HIVR01DA013336 · NIDA · NATIONAL DEVELOPMENT &RES INSTITUTES · PI COOPER, HANNAH LF, FRIEDMAN, SAMUEL R · 2000 to 2013
$7.6M
NIDA NIH HHS 5T32 DA007233NIDA NIH HHS R01 DA 003574NIDA NIH HHS R01 DA003574NIDA NIH HHS R01 DA013336NIDA NIH HHS T32 DA007233
6 · The paper itself

Abstract

purposeWe focus on a little-researched issue-how human immunodeficiency virus (HIV) epidemics and programs in key populations in metropolitan areas affect epidemics in other key populations. We consider (1) How are earlier epidemics among people who inject drugs (PWID) and men who have sex with men (MSM) related to later AIDS incidence and mortality among heterosexuals?; (2) Were prevention programs targeting PWID or MSM associated with lower AIDS incidence and mortality among heterosexuals?; and (3) Was the size of the potential bridge population of noninjecting drug users (NIDUs) in a metropolitan area associated with later AIDS incidence and mortality among heterosexuals?

methodsUsing data for 96 large U.S. metropolitan areas, Poisson regression assessed associations of population prevalences of HIV-infected PWID and MSM (1992); NIDU population prevalence (1992-1994); drug use treatment coverage for PWID (1993); HIV counseling and testing coverage for MSM and for PWID (1992); and syringe exchange presence (2000) with CDC data on AIDS incidence and mortality among heterosexuals in 2006-2008, with appropriate socioeconomic controls.

resultsPopulation density of HIV+ PWID and of NIDUs were positively related, and prevention programs for PWID negatively related to later AIDS incidence among heterosexuals and later mortality among heterosexuals living with AIDS. HIV+ MSM population density and prevention programs for MSM were not associated with these outcomes.

conclusionsEfforts to reduce HIV transmission among PWID and NIDUs may reduce AIDS and AIDS-related mortality among heterosexuals. More research is needed at metropolitan area, network, and individual levels into HIV bridging across key populations and how interventions in one key population affect HIV epidemics in other key populations.

Indexed as

HeterosexualityHomosexuality, MaleSubstance Abuse, IntravenousUrban PopulationAcquired Immunodeficiency SyndromeAdolescentAdultCohort StudiesHIV SeroprevalenceHumansMaleMiddle AgedPoisson DistributionUnited StatesYoung AdultBridgingEpidemicsHeterosexualsHIV/AIDSIDUMen who have sex with menMetropolitan areasMSMPeople who inject drugsUrban health

Identifiers

PMID24529517
PMCPMC3954755
OpenAlexW2148802229

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.