ArticleMethods in enzymology2014
Measurement of long-chain fatty acid uptake into adipocytes.
Article in Methods in enzymology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- Near-infrared fatty acid molecular probe for image-guided surgery of glioblastoma.Npj imaging · 2025Article
- Metabolic dependencies of metastasis-initiating cells in female breast cancer.Nature communications · 2023Article
- Lipid droplets are a metabolic vulnerability in melanoma.Nature communications · 2023Article
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- Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice.The Journal of clinical investigation · 2022Article
- Controlling the polarity of human gastrointestinal organoids to investigate epithelial biology and infectious diseases.Nature protocols · 2021Review
- Chemerin regulates formation and function of brown adipose tissue: Ablation results in increased insulin resistance with high fat challenge and aging.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- NT-PGC-1α deficiency attenuates high-fat diet-induced obesity by modulating food intake, fecal fat excretion and intestinal fat absorption.Scientific reports · 2021Article
- Fatty-Acid Uptake in Prostate Cancer Cells Using Dynamic Microfluidic Raman Technology.Molecules (Basel, Switzerland) · 2020Article
- Highly Glycolytic Immortalized Human Dermal Microvascular Endothelial Cells are Able to Grow in Glucose-Starved Conditions.Biomolecules · 2019Article
- Targeting RalGAPα1 in skeletal muscle to simultaneously improve postprandial glucose and lipid control.Science advances · 2019Article
- Metabolic Syndrome is Associated with Ceramide Accumulation in Visceral Adipose Tissue of Women with Morbid Obesity.Obesity (Silver Spring, Md.) · 2019Article
- [Scientific reports · 2019Article
- Cell culture models of fatty acid overload: Problems and solutions.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2018Review
- Fatty Acid Uptake in T Cell Subsets Using a Quantum Dot Fatty Acid Conjugate.Scientific reports · 2017Article
- The coccidian parasitesThe Journal of biological chemistry · 2017Article
- Automated Microfluidic Droplet-Based Sample Chopper for Detection of Small Fluorescence Differences Using Lock-In Analysis.Analytical chemistry · 2017Article
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Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
The ability of white and brown adipose tissue to efficiently take up long-chain fatty acids is key to their physiological functions in energy storage and thermogenesis, respectively. Several approaches have been taken to determine uptake rates by cultured cells and primary adipocytes including radio- and fluorescently labeled fatty acids. In addition, the recent description of activatable bioluminescent fatty acids has opened the possibility for expanding these in vitro approaches to real-time monitoring of fatty acid uptake kinetics by adipose depots in vivo. Here, we will describe some of the most useful experimental paradigms to quantitatively determine long-chain fatty acid uptake by adipocytes in vitro and provide the reader with detailed instruction on how bioluminescent probes for in vivo imaging can be synthesized and used in living mice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.