Evidence map›Paper›PMID 24529254›Full record

ReviewCurrent opinion in cell biology2014

The Chromosomal Courtship Dance-homolog pairing in early meiosis.

Michael Klutstein, Julia Promisel Cooper

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Identifying Chromosome Movement Patterns During Meiosis Using ChroMo.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Cyclins and CDKs in the regulation of meiosis-specific events.Frontiers in cell and developmental biology · 2022
    Review
  10. Article
  11. Article
  12. Recombination-independent recognition of DNA homology for meiotic silencing inProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Cells · 2021
    Article
  14. Article
  15. Article
  16. Meiotic Chromosome Dynamics in Zebrafish.Frontiers in cell and developmental biology · 2021
    Review
  17. Chromosome Organization in Early Meiotic Prophase.Frontiers in cell and developmental biology · 2021
    Review
  18. Regulation of Meiotic Prophase One in Mammalian Oocytes.Frontiers in cell and developmental biology · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Michael KlutsteinCancer Research UK, London Research Institute, NIH, London WC2A 3LY, United Kingdom; National Cancer Institute, NIH, Bethesda, MD 20892, United States.
Julia Promisel CooperCancer Research UK, London Research Institute, NIH, London WC2A 3LY, United Kingdom; National Cancer Institute, NIH, Bethesda, MD 20892, United States. Electronic address: julie.cooper@nih.gov.
Cancer Research UK · GB

Funding

Telomere BiologyZIABC011519 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI COOPER, JULIA · 2013 to 2020
$13.1M
Cancer Research UKIntramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

The intermingling of genomes that characterizes sexual reproduction requires haploid gametes in which parental homologs have recombined. For this, homologs must pair during meiosis. In a crowded nucleus where sequence homology is obscured by the enormous scale and packaging of the genome, partner alignment is no small task. Here we review the early stages of this process. Chromosomes first establish an initial docking site, usually at telomeres or centromeres. The acquisition of chromosome-specific patterns of binding factors facilitates homolog recognition. Chromosomes are then tethered to the nuclear envelope (NE) and subjected to nuclear movements that 'shake off' inappropriate contacts while consolidating homolog associations. Thereafter, homolog connections are stabilized by building the synaptonemal complex or its equivalent and creating genetic crossovers. Recent perspectives on the roles of these stages will be discussed.

Indexed as

Chromosome PairingChromosomesMeiosisAnimalsCell NucleusHumansRNARNA

Identifiers

PMID24529254
PMCPMC6329632
OpenAlexW2085188271

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.