Evidence map›Paper›PMID 24529000›Full record

ArticleEnvironmental research2014

Urinary concentrations of environmental phenols in pregnant women in a pilot study of the National Children's Study.

Mary E Mortensen, Antonia M Calafat, Xiaoyun Ye, Lee-Yang Wong, David J Wright, James L Pirkle, Lori S Merrill, John Moye

Abstract read
In one paragraph

Article in Environmental research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 128 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mary E MortensenNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: MMortensen@cdc.gov.
Antonia M CalafatNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Xiaoyun YeNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Lee-Yang WongNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
David J WrightWestat, Inc. Rockville, MD, USA.
James L PirkleNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Lori S MerrillWestat, Inc. Rockville, MD, USA.
John MoyeNCS Program Office, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes for Health, Bethesda, MD, USA.
National Center for Environmental Health · USWestat (United States) · USCenters for Disease Control and Prevention · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Environmental phenols are a group of chemicals with widespread uses in consumer and personal care products, food and beverage processing, and in pesticides. We assessed exposure to benzophenone-3, bisphenol A (BPA), triclosan, methyl- and propyl parabens, and 2,4- and 2,5-dichlorophenol or their precursors in 506 pregnant women enrolled in the National Children's Study (NCS) Vanguard Study. We measured the urinary concentrations of the target phenols by using online solid-phase extraction-isotope dilution high performance liquid chromatography-tandem mass spectrometry. NCS women results were compared to those of 524 similar-aged women in the National Health and Nutrition Examination Survey (NHANES) 2009-2010, and to 174 pregnant women in NHANES 2005-2010. In the NCS women, we found significant racial/ethnic differences (p<0.05) in regression adjusted mean concentrations of benzophenone-3, triclosan, 2,4- and 2,5-dichlorophenol, but not of BPA. Urinary 2,4- and 2,5-dichlorophenol concentrations were highly correlated (r=0.66, p<0.0001). Except for BPA and triclosan, adjusted mean concentrations were significantly different across the 7 study sites. Education was marginally significant for benzophenone-3, triclosan, propyl paraben, and 2,5-dichlorophenol. Urinary concentrations of target phenols in NCS pregnant women and U.S. women and pregnant women were similar. In NCS pregnant women, race/ethnicity and geographic location determined urinary concentrations of most phenols (except BPA), suggesting differential exposures. NCS Main Study protocols should collect urine biospecimens and information about exposures to environmental phenols.

Indexed as

AdolescentAdultChildChild DevelopmentChromatography, High Pressure LiquidEnvironmental ExposureEnvironmental MonitoringEnvironmental PollutantsFemaleFinancing, GovernmentHumansMiddle AgedPhenolsPilot ProjectsPregnancyPrenatal Exposure Delayed EffectsEnvironmental PollutantsPhenolsBiomonitoringEnvironmental phenolsNational children's studyNational health and nutrition examination surveyPregnancy

Identifiers

PMID24529000
PMCPMC4530794
OpenAlexW2061933800

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.