Evidence map›Paper›PMID 24528859›Full record

ArticleCell host & microbe2014

Influenza A virus lures autophagic protein LC3 to budding sites.

Christian Münz

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Autophagy in Negative-Strand RNA Virus Infection.Frontiers in microbiology · 2018
    Review
  5. Review
  6. Influenza A Virus M2 Protein: Roles from Ingress to Egress.International journal of molecular sciences · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Christian MünzViral Immunobiology, Institute of Experimental Immunology, University of Zürich, 8057 Zürich, Switzerland. Electronic address: christian.muenz@uzh.ch.

Funding

Medical Research Council G0700815
6 · The paper itself

Abstract

Autophagy, a cellular degradation pathway, can restrict or assist viral replication. In this issue of Cell Host & Microbe, Beale et al. (2014) report that the influenza virus matrix protein 2 binds to the essential autophagy protein LC3 to presumably transport LC3-conjugated membranes to the cell surface for budding of stable viruses.

Indexed as

AutophagyHost-Pathogen InteractionsProtein Interaction Domains and MotifsInfluenza A virusMicrotubule-Associated ProteinsViral Matrix ProteinsVirionViroporin ProteinsM2 protein, Influenza A virusMAP1LC3A protein, humanMicrotubule-Associated ProteinsViral Matrix ProteinsViroporin Proteins

Identifiers

PMID24528859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.