Evidence map›Paper›PMID 24528626›Full record

ReviewCardiovascular diabetology2014

Cardiovascular microRNAs: as modulators and diagnostic biomarkers of diabetic heart disease.

Shruti Rawal, Patrick Manning, Rajesh Katare

Open access · goldAbstract readReview
In one paragraph

Review in Cardiovascular diabetology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 107 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Circular RNAs: a small piece in the heart failure puzzle.Functional & integrative genomics · 2024
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Sestrin2 in diabetes and diabetic complications.Frontiers in endocrinology · 2023
    Review
  13. Review
  14. Exosomal microRNAs in diabetic heart disease.Cardiovascular diabetology · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shruti Rawal
Patrick Manning
Rajesh KatareDepartment of Physiology, HeartOtago, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand. rajesh.katare@otago.ac.nz.
University of Otago · NZDunedin Public Hospital · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic heart disease (DHD) is the leading cause of morbidity and mortality among the people with diabetes, with approximately 80% of the deaths in diabetics are due to cardiovascular complications. Importantly, heart disease in the diabetics develop at a much earlier stage, although remaining asymptomatic till the later stage of the disease, thereby restricting its early detection and active therapeutic management. Thus, a better understanding of the modulators involved in the pathophysiology of DHD is necessary for the early diagnosis and development of novel therapeutic implications for diabetes-associated cardiovascular complications. microRNAs (miRs) have recently been evolved as key players in the various cardiovascular events through the regulation of cardiac gene expression. Besides their credible involvement in controlling the cellular processes, they are also released in to the circulation in disease states where they serve as potential diagnostic biomarkers for cardiovascular disease. However, their potential role in DHD as modulators as well as diagnostic biomarkers is largely unexplored. In this review, we describe the putative mechanisms of the selected cardiovascular miRs in relation to cardiovascular diseases and discuss their possible involvement in the pathophysiology and early diagnosis of DHD.

Indexed as

AnimalsBiomarkersCardiovascular DiseasesDiabetes ComplicationsDiabetes MellitusHeart DiseasesHumansMicroRNAsBiomarkersMicroRNAs

Identifiers

PMID24528626
PMCPMC3976030
OpenAlexW1995085194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.