Evidence map›Paper›PMID 24527415›Full record

ArticleClinical nutrition research2014

Basophil activation test with food additives in chronic urticaria patients.

Min-Gyu Kang, Woo-Jung Song, Han-Ki Park, Kyung-Hwan Lim, Su-Jung Kim, Suh-Young Lee, Sae-Hoon Kim, Sang-Heon Cho, Kyung-Up Min, Yoon-Seok Chang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical nutrition research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Min-Gyu KangDepartment of Internal Medicine, Seoul National University College of Medicine 110-744, Seoul, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center 110-744, Seoul, Korea. ; Division of Allergy and Clinical Immunology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 463-707, Korea.
Woo-Jung SongDepartment of Internal Medicine, Seoul National University College of Medicine 110-744, Seoul, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center 110-744, Seoul, Korea.
Han-Ki ParkDepartment of Internal Medicine, Seoul National University College of Medicine 110-744, Seoul, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center 110-744, Seoul, Korea.
Kyung-Hwan LimDepartment of Internal Medicine, Seoul National University College of Medicine 110-744, Seoul, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center 110-744, Seoul, Korea. ; Division of Allergy and Clinical Immunology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 463-707, Korea.
Su-Jung KimDepartment of Internal Medicine, Seoul National University College of Medicine 110-744, Seoul, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center 110-744, Seoul, Korea.
Suh-Young LeeDepartment of Internal Medicine, Seoul National University College of Medicine 110-744, Seoul, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center 110-744, Seoul, Korea.
Sae-Hoon KimDepartment of Internal Medicine, Seoul National University College of Medicine 110-744, Seoul, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center 110-744, Seoul, Korea. ; Division of Allergy and Clinical Immunology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 463-707, Korea.
Sang-Heon ChoDepartment of Internal Medicine, Seoul National University College of Medicine 110-744, Seoul, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center 110-744, Seoul, Korea.
Kyung-Up MinDepartment of Internal Medicine, Seoul National University College of Medicine 110-744, Seoul, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center 110-744, Seoul, Korea.
Yoon-Seok ChangDepartment of Internal Medicine, Seoul National University College of Medicine 110-744, Seoul, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center 110-744, Seoul, Korea. ; Division of Allergy and Clinical Immunology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 463-707, Korea.ORCID 0000-0003-3157-0447
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of food additives in chronic urticaria (CU) is still under investigation. In this study, we aimed to explore the association between food additives and CU by using the basophil activation test (BAT). The BAT using 15 common food additives was performed for 15 patients with CU who had a history of recurrent urticarial aggravation following intake of various foods without a definite food-specific IgE. Of the 15 patients studied, two (13.3%) showed positive BAT results for one of the tested food additives. One patient responded to monosodium glutamate, showing 18.7% of CD203c-positive basophils. Another patient showed a positive BAT result to sodium benzoate. Both patients had clinical correlations with the agents, which were partly determined by elimination diets. The present study suggested that at least a small proportion of patients with CU had symptoms associated with food additives. The results may suggest the potential utility of the BAT to identity the role of food additives in CU.

Indexed as

Basophil activation testFood additivesHypersensitivityMonosodium glutamateSodium benzoateUrticaria

Identifiers

PMID24527415
PMCPMC3921299
OpenAlexW2002136949

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.