Evidence map›Paper›PMID 24527404›Full record

ReviewAsia Pacific allergy2014

Changing the paradigm for cough: does 'cough hypersensitivity' aid our understanding?

Woo-Jung Song, Yoon-Seok Chang, Alyn H Morice

Abstract readReview
In one paragraph

Review in Asia Pacific allergy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Speech and language therapy for management of chronic cough.The Cochrane database of systematic reviews · 2019
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. State of the Art for Refractory Cough: Multidisciplinary Approach.Tuberculosis and respiratory diseases · 2023
    Article
  7. Article
  8. Management of chronic refractory cough in adults.European journal of internal medicine · 2020
    Review
  9. Review
  10. Review
  11. Cough Hypersensitivity Syndrome: A Few More Steps Forward.Allergy, asthma & immunology research · 2017
    Review
  12. Article
  13. Observational
  14. Review
  15. Greetings fromAsia Pacific allergy · 2016
    Article
  16. Article
  17. Review
  18. Cough hypersensitivity as a neuro-immune interaction.Clinical and translational allergy · 2015
    Review
  19. Article
  20. Asia Pacific, and beyond.Asia Pacific allergy · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Woo-Jung SongDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea.
Yoon-Seok ChangDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea. ; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 463-707, Korea.ORCID 0000-0003-3157-0447
Alyn H MoriceCardiovascular and Respiratory Studies, Castle Hill Hospital, University of Hull, Hull York Medical School, Cottingham HU16 5JQ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic cough is a common reason for patients to seek medication attention. Over the last few decades, we have experienced significant clinical success by applying the paradigm of 'evaluating and treating the causes for chronic cough'. However, we still ask ourselves 'what underlies chronic cough. Indeed in a considerable proportion of patients cough is idiopathic, or unexplained despite vigorous evaluation. Commonly associated conditions such as rhinitis, eosinophilic bronchitis, asthma, or gastroesophageal acidic reflux may not be fundamental to cough, and thus may be triggers rather than causes. The cardinal feature of chronic cough is persistent upregulation the cough reflex, which may be driven by complex interactions between biologic, neurologic, immunologic, genetic, comorbid, and environmental factors. We suggest the new paradigm 'cough hypersensitivity syndrome' should finally bring us further advances in understanding and management of chronic cough.

Indexed as

CoughEtiologyPathophysiologyRespiratory hypersensitivity

Identifiers

PMID24527404
PMCPMC3921869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.