Evidence map›Paper›PMID 24527269›Full record

ArticleTranslational medicine (Sunnyvale, Calif.)2012

Molecular Targeted Therapies Using Botanicals for Prostate Cancer Chemoprevention.

Nagi Kumar, Ganna Chornokur

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational medicine (Sunnyvale, Calif.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nagi KumarDepartment of Epidemiology, H. Lee Moffitt Cancer Center & Research Institute, Florida, USA ; University of South Florida College of Medicine, Florida, USA.
Ganna ChornokurDepartment of Epidemiology, H. Lee Moffitt Cancer Center & Research Institute, Florida, USA.
Moffitt Cancer Center · US

Funding

USF/Moffitt Transdisciplinary Center to Address Cancer Health DisparitiesP20MD003375 · NIMHD · UNIVERSITY OF SOUTH FLORIDA · PI JACOBSEN, PAUL B · 2009 to 2013
$7.3M
Phase II Clinical Trial of Polyphenon E in Prostate CancerR01CA122060 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI KUMAR, NAGI B. · 2007 to 2011
$4.0M
Neural mechanisms of sound activation of vestibular systemR01DC012060 · NIDCD · UNIVERSITY OF MISSISSIPPI MED CTR · PI ZHU, HONG · 2012 to 2016
$1.9M
NCI NIH HHS R01 CA122060NIDCD NIH HHS R01 DC012060NIMHD NIH HHS P20 MD003375
6 · The paper itself

Abstract

In spite of the large number of botanicals demonstrating promise as potential cancer chemopreventive agents, most have failed to prove effectiveness in clinical trials. Critical requirements for moving botanical agents to recommendation for clinical use include adopting a systematic, molecular-target based approach and utilizing the same ethical and rigorous methods that are used to evaluate other pharmacological agents. Preliminary data on a mechanistic rationale for chemoprevention activity as observed from epidemiological,

Indexed as

ChemopreventionCurcuminDecursinGreen Tea Polyphenols (GTP)IsoflavonesProstate cancer

Identifiers

PMID24527269
PMCPMC3920581
OpenAlexW2021553795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.