SAMHD1: a new gene for CLL.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia.Blood cancer journal · 2018
   Trial
2. Cellular pharmacology of fludarabine: molecular determinants of transport and metabolism.Frontiers in pharmacology · 2026
   Review
3. Deoxyguanosine-Linked Bifunctional Inhibitor of SAMHD1 dNTPase Activity and Nucleic Acid Binding.ACS chemical biology · 2023
   Article
4. Direct and indirect effects of IFN-α2b in malignancy treatment: not only an archer but also an arrow.Biomarker research · 2022
   Review
5. Expression of SAMHD1 and its mutation on prognosis of colon cancer.Oncology letters · 2022
   Article
6. Metabolism, Biochemical Actions, and Chemical Synthesis of Anticancer Nucleosides, Nucleotides, and Base Analogs.Chemical reviews · 2016
   Review
7. Deoxyribonucleotide metabolism, mutagenesis and cancer.Nature reviews. Cancer · 2015
   Review
8. Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance.Cell host & microbe · 2015
   Article
9. Structural basis of cellular dNTP regulation by SAMHD1.Proceedings of the National Academy of Sciences of the United States of America · 2014
   Article
10. Mouse knockout models for HIV-1 restriction factors.Cellular and molecular life sciences : CMLS · 2014
    Review

Corrections and comments

• Comment on
  SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.2014

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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