Evidence map›Paper›PMID 24526695›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2014

Regulation of an inflammatory disease: Krüppel-like factors and atherosclerosis.

Mukesh K Jain, Panjamaporn Sangwung, Anne Hamik

Abstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Resilience to diabetic retinopathy.Progress in retinal and eye research · 2024
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. The MEK5/ERK5 Pathway in Health and Disease.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mukesh K JainFrom the Case Cardiovascular Research Institute, Case Western Reserve University, Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH (M.K.J., P.S., A.H.); and Division of Cardiovascular Medicine, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH (A.H.).
Panjamaporn Sangwung
Anne Hamik

Funding

KLF2, monocyte activation and vascular inflammationR01HL086548 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JAIN, MUKESH KUMAR · 2007 to 2016
$3.5M
KLF2 as a regulator of endothelial cell biologyR01HL076754 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JAIN, MUKESH KUMAR · 2004 to 2012
$3.2M
KLF4 and Transcriptional Control of NeovascularizationR01HL113570 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI HAMIK, ANNE · 2013 to 2017
$1.9M
KLF15 in vascular diseaseR01HL112486 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JAIN, MUKESH KUMAR · 2012 to 2015
$1.9M
KLF4 , the endothelium, and vascular inflammationR01HL097593 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JAIN, MUKESH KUMAR · 2010 to 2013
$1.5M
KLF4 and Myeloid Cell BiologyR01HL110630 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JAIN, MUKESH KUMAR · 2011 to 2014
$1.5M
NHLBI NIH HHS HL076754NHLBI NIH HHS HL086548NHLBI NIH HHS HL097593NHLBI NIH HHS HL110630NHLBI NIH HHS HL112486NHLBI NIH HHS HL113570NHLBI NIH HHS R01 HL076754NHLBI NIH HHS R01 HL086548NHLBI NIH HHS R01 HL097593NHLBI NIH HHS R01 HL110630NHLBI NIH HHS R01 HL112486NHLBI NIH HHS R01 HL113570
6 · The paper itself

Abstract

This invited review summarizes work presented in the Russell Ross lecture delivered at the 2012 proceedings of the American Heart Association. We begin with a brief overview of the structural, cellular, and molecular biology of Krüppel-like factors. We then focus on discoveries during the past decade, implicating Krüppel-like factors as key determinants of vascular cell function in atherosclerotic vascular disease.

Indexed as

AnimalsAtherosclerosisDisease ProgressionDNAEndothelial CellsEndothelium, VascularFoam CellsGene Expression RegulationHemorheologyHumansInflammationKruppel-Like Transcription FactorsLymphocyte SubsetsMiceMice, KnockoutModels, CardiovascularDNAKruppel-Like Transcription FactorsNuclear ProteinsatherosclerosisKrüppel-like transcription factors

Identifiers

PMID24526695
PMCPMC5539879

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.