ReviewCurrent psychiatry reports2014
The complicated relationship between attention deficit/hyperactivity disorder and substance use disorders.
Review in Current psychiatry reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 6 syntheses or guidelines pooled it, 216 citations in OpenAlex.
- Maternal and offspring outcomes associated with prescribed ADHD medication in pregnancy: a systematic review.Archives of women's mental health · 2025Pooled it
- Diminished Interoceptive Accuracy in Attention-Deficit/Hyperactivity Disorder: A Systematic Review.Psychophysiology · 2025Pooled it
- Prevalence of Attention Deficit Hyperactivity Disorder (ADHD) among Substance Use Disorder (SUD) Populations: Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Global Economic Burden of Attention-Deficit/Hyperactivity Disorder: A Systematic Review.PharmacoEconomics · 2021Pooled it
- The ASAM/AAAP Clinical Practice Guideline on the Management of Stimulant Use Disorder.Journal of addiction medicineGuideline
- Pharmacological Treatment of ADHD in Addicted Patients: What Does the Literature Tell Us?Harvard review of psychiatryPooled it
- Achieving cannabis cessation -- evaluating N-acetylcysteine treatment (ACCENT): design and implementation of a multi-site, randomized controlled study in the National Institute on Drug Abuse Clinical Trials Network.Contemporary clinical trials · 2014Trial
- Posterior spinal fusion outcomes in adolescent idiopathic scoliosis patients with attention deficit hyperactivity disorder (ADHD): ADHD subtype makes a difference.Spine deformity · 2026Article
- Factors Associated with Reduced Clinical Response in Adult ADHD: The Role of Alcohol and Cannabis Use Disorders and Autism Spectrum Disorder.Journal of clinical medicine · 2026Article
- Self-Reported ADHD Diagnosis and Illicit Drug Use and Prescription Medication Misuse Among U.S. Working-Age Adults.Journal of attention disorders · 2025Article
- Prenatal environmental risk for adolescent attention, thought, and substance use problems: A mixtures approach to coexposure and psychiatric comorbidities.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Fueling the Cycle: Attachment, Cognition, and Emotion in Substance-Using Incarcerated Young Adults.Clinical neuropsychiatry · 2025Article
- The Interplay Between Juvenile Delinquency and ADHD: A Systematic Review of Social, Psychological, and Educational Aspects.Behavioral sciences (Basel, Switzerland) · 2025Review
- Comparing Obstetrical Outcomes Between Attention Deficit Hyperactivity Disorder and Attention Deficit Disorder: A Population-Based Studys.Journal of clinical medicine · 2025Article
- Unraveling Attention-Deficit/Hyperactivity Disorder Etiology: Current Challenges and Future Directions in Treatment.NeuroSci · 2025Review
- Validity of the Italian Version of DIVA-5: Semi-Structured Diagnostic Interview for Adult ADHD Based on the DSM-5 Criteria.Healthcare (Basel, Switzerland) · 2025Article
- Psychosocial interventions for improving the physical health of young people and adults with attention deficit hyperactivity disorder: a scoping review.BMC psychiatry · 2024Article
- Attention-Deficit Hyperactivity Disorder Stimulant Therapy and Prescription Drug Misuse During Transition to Young Adulthood.Psychiatric services (Washington, D.C.) · 2024Article
- Attention Deficit Hyperactivity Disorder: A Risk Factor for Premature Discontinuation of Inpatient Opioid Withdrawal Treatment.Journal of clinical medicine · 2024Article
- Genetic contribution to the comorbidity between attention-deficit/hyperactivity disorder and substance use disorders.Psychiatry research · 2024Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Adolescents and young adults with substance use disorders (SUD) and attention deficit/hyperactivity disorder (ADHD) are increasingly presenting in clinical practice. The overlap and role of treatment for these co-occurring disorders remains unclear. A review of the literature was conducted to highlight and update recent evidence on the overlap of ADHD and SUD, the role of ADHD medication on later SUD, and the treatment of ADHD and SUD in adolescents and young adults. Recent work continues to highlight the high risk for comorbid ADHD in patients with SUD; and conversely, the high risk for SUD developing in ADHD across the lifespan, particularly in the context of comorbid conduct disorder. Although the data remains discordant, it appears that ADHD pharmacotherapy does not increase the risk for SUD. Medication treatment alone does not appear to be particularly effective in treating SUD in currently active substance abusing individuals with ADHD. Structured therapies may be effective in treating adolescents and young adults with ADHD and SUD. Further controlled trials evaluating the sequence and effect of structured psychotherapies and/or ADHD pharmacotherapy on SUD relapse in these groups are warranted.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.