Evidence map›Paper›PMID 24525865›Full record

ArticleEye (London, England)2014

Influence of diabetes and diabetes type on anatomic and visual outcomes following central rein vein occlusion.

J G Santiago, S Walia, J K Sun, J D Cavallerano, Z A Haddad, L P Aiello, P S Silva

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Eye (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Baseline clinical features predict visual outcome in young patients with central retinal vein occlusion.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  4. Article
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

J G SantiagoBeetham Eye Institute, Joslin Diabetes Center, Boston, MA, USA.
S WaliaBeetham Eye Institute, Joslin Diabetes Center, Boston, MA, USA.
J K Sun1] Beetham Eye Institute, Joslin Diabetes Center, Boston, MA, USA [2] Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
J D Cavallerano1] Beetham Eye Institute, Joslin Diabetes Center, Boston, MA, USA [2] Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Z A HaddadBeetham Eye Institute, Joslin Diabetes Center, Boston, MA, USA.
L P Aiello1] Beetham Eye Institute, Joslin Diabetes Center, Boston, MA, USA [2] Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
P S Silva1] Beetham Eye Institute, Joslin Diabetes Center, Boston, MA, USA [2] Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Joslin Diabetes Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the influence of diabetes and diabetes type on ocular outcomes following central retinal vein occlusion (CRVO).

methodsRetrospective chart review of all patients evaluated over a 4-year period in a tertiary diabetes eye care center. Ophthalmic findings were recorded including visual acuity and the presence of retinal neovascularization at presentation, after 3-6 months, and at last follow-up.

resultsThe records of 19,648 patients (13,571 diabetic; 6077 nondiabetic) were reviewed. The prevalence of CRVO in diabetic patients (N=72) and nondiabetic patients (N=27) were 0.5 and 0.4%, respectively. Disc neovascularization (21.3 vs 0.0%, P=0.05) and panretinal photocoagulation (PRP) (48.7 vs 21.4%, P=0.01) were more common in diabetic patients compared with nondiabetic patients. Compared with type 2 diabetic patients, retinal neovascularization (28.6 vs 3.7%, P=0.004) and subsequent PRP (78.6 vs 41.9%, P=0.01) were more likely in type 1 patients. Optic nerve head collateral vessels (CVs) were observed less than half as often (21.4 vs 56.5%, P=0.04) in patients with type 1 diabetes. Presence of optic nerve head CVs at baseline was associated with less likelihood of PRP (14.3 vs 46.1%, P=0.03).

conclusionsIn this cohort, the rates of CRVO in diabetic and nondiabetic patients were similar to previously published population-based studies. Following CRVO, diabetic patients had higher rates of disc neovascularization and were more likely to require subsequent PRP than nondiabetic patients. As compared with CRVO patients with type 2 diabetes, patients with type 1 diabetes and CRVO had worse anatomic outcomes with substantially increased risks of retinal neovascularization and PRP; however, final visual acuity outcomes were similar.

Indexed as

AdultAgedAged, 80 and overDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic RetinopathyFemaleFluorescein AngiographyGlaucoma, Open-AngleHumansIntraocular PressureLaser CoagulationMaleMiddle AgedRetinal NeovascularizationRetinal Vein Occlusion

Identifiers

PMID24525865
PMCPMC3965828
OpenAlexW1985036882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.