Evidence map›Paper›PMID 24525784›Full record

ArticleCell research2014

Histone glutamine methylation afFACTing rDNA transcription.

Heinrich Leonhardt, Sandra B Hake

Open access · bronzeAbstract readComment
In one paragraph

Article in Cell research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Heinrich LeonhardtDepartment of Biology II, Humanbiology and Bioimaging, Center for Integrated Protein Science (CIPSM), Ludwig Maximilians University Munich, 82152 Planegg-Martinsried, Germany.
Sandra B HakeMolecular Biology Unit, Adolf-Butenandt-Institute, Center for Integrated Protein Science Munich (CIPSM), Ludwig Maximilians University Munich, 80336 Munich, Germany.
Center for Integrated Protein Science Munich · DE

Funding

Biotechnology and Biological Sciences Research Council BB/K017438/1
6 · The paper itself

Abstract

Chemical modifications of histone proteins directly and indirectly affect chromatin structure and thereby contribute to the multilayered control of diverse DNA-based processes. A recent study in Nature enriches this list of enzyme-dependent posttranslational histone marks by H2A glutamine methylation that appears to be dedicated to only one specific cellular process, the regulation of nucleolar rDNA transcription.

Indexed as

GlutamineHistonesHumansRNA Polymerase IGlutamineHistonesRNA Polymerase I

Identifiers

PMID24525784
PMCPMC3945891
OpenAlexW2008186540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.