ArticleParasitology research2014
Genotype analysis of T. gondii strains associated with human infection in Egypt.
Article in Parasitology research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An African perspective on the genetic diversity ofParasitology · 2023Pooled it
- Is GRA6 Gene a Suitable Marker for Molecular Typing of Toxoplasma Gondii? A Scoping Systematic Review.Acta parasitologica · 2024Article
- Seroprevalence and Genetic Characterization ofJournal of tropical medicine · 2022Article
- Temporal expression of Toxoplasma stage-specific genes in brain tissue: coincidence with parasitological and histopathological findings in mice models.Parasitology research · 2020Article
- A review on toxoplasmosis in humans and animals from Egypt.Parasitology · 2020Review
- Toxoplasma genotyping in congenital toxoplasmosis in Upper Egypt: evidence of type I strain.Parasitology research · 2017Article
- Transcriptomic analysis of global changes in cytokine expression in mouse spleens following acute Toxoplasma gondii infection.Parasitology research · 2016Article
- Seroprevalence and risk factors of Toxoplasma gondii infection in stray dogs in northern China.Parasitology research · 2015Article
- A long-lasting protective immunity against chronic toxoplasmosis in mice induced by recombinant rhoptry proteins encapsulated in poly (lactide-co-glycolide) microparticles.Parasitology research · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The distribution of Toxoplasma gondii genotypes varies from one geographic area to another. The present study aimed to determine T. gondii genotypes associated with human infection in Egypt. Individuals seropositive for anti-toxoplasma IgG and IgM (group I, n = 50) or for specific IgG only (group II, n = 50) were enrolled. Of the participants, 75 % were asymptomatic pregnant women. The others presented with lymphadenitis (n = 21), chorioretinitis (n = 3), and unexplained hepatomegaly (n = 1). Using nested PCR, T. gondii GRA6-coding fragment was amplified from DNA extracted from blood samples of participants. Amplification was successful in 12 samples with nonsignificant difference between both groups but with a significant association with the presence of toxoplasmosis-related manifestations. Restriction fragment length polymorphism analysis of these samples revealed the presence of type I in seven samples and atypical types in five samples. Both typical and atypical strains were detected in individuals of both groups with no bias towards specific clinical presentation.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.