Evidence map›Paper›PMID 24525327›Full record

ArticleJournal of neuroscience methods2014

High resolution MRI anatomy of the cat brain at 3 Tesla.

Heather L Gray-Edwards, Nouha Salibi, Eleanor M Josephson, Judith A Hudson, Nancy R Cox, Ashley N Randle, Victoria J McCurdy, Allison M Bradbury, Diane U Wilson, Ronald J Beyers and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of neuroscience methods, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  4. Beyond the surface: howFrontiers in neuroscience · 2024
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  7. Cranial Investigations of Crested Porcupine (Animals : an open access journal from MDPI · 2023
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  9. Frontiers in neuroanatomy · 2022
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  11. GM1 Gangliosidosis: Mechanisms and Management.The application of clinical genetics · 2021
    Review
  12. Article
  13. Article
  14. The Brain Anatomy of the Brown Bear (Carnivora,Frontiers in neuroanatomy · 2019
    Article
  15. Article
  16. A monocentric centerline extraction method for ring-like blood vessels.Medical & biological engineering & computing · 2018
    Article
  17. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Heather L Gray-EdwardsScott-Ritchey Research Center, Auburn University, Auburn, AL, United States. Electronic address: grayhea@auburn.edu.
Nouha SalibiMR R&D Siemens Healthcare, Malvern, PA, United States.
Eleanor M JosephsonDepartment of Anatomy, Physiology and Pharmacology, Auburn University, Auburn, AL, United States.
Judith A HudsonDepartment of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Nancy R CoxScott-Ritchey Research Center, Auburn University, Auburn, AL, United States.
Ashley N RandleScott-Ritchey Research Center, Auburn University, Auburn, AL, United States.
Victoria J McCurdyScott-Ritchey Research Center, Auburn University, Auburn, AL, United States; Department of Anatomy, Physiology and Pharmacology, Auburn University, Auburn, AL, United States.
Allison M BradburyScott-Ritchey Research Center, Auburn University, Auburn, AL, United States; Department of Anatomy, Physiology and Pharmacology, Auburn University, Auburn, AL, United States.
Diane U WilsonScott-Ritchey Research Center, Auburn University, Auburn, AL, United States.
Ronald J BeyersAuburn University MRI Research Center, Auburn, AL, United States.
Thomas S DenneyDepartment of Electrical and Computer Engineering, Auburn University, Auburn, AL, United States; Auburn University MRI Research Center, Auburn, AL, United States.
Douglas R MartinScott-Ritchey Research Center, Auburn University, Auburn, AL, United States; Department of Anatomy, Physiology and Pharmacology, Auburn University, Auburn, AL, United States.
Auburn University · USSiemens Healthcare (United States) · US

Funding

In vivo magnetic resonance-based analysis of inherited neurologic disease after gF32NS080488 · NINDS · AUBURN UNIVERSITY AT AUBURN · PI GRAY-EDWARDS, HEATHER L · 2013 to 2015
$196k
NINDS NIH HHS F32 NS080488
6 · The paper itself

Abstract

backgroundFeline models of neurologic diseases, such as lysosomal storage diseases, leukodystrophies, Parkinson's disease, stroke and NeuroAIDS, accurately recreate many aspects of human disease allowing for comparative study of neuropathology and the testing of novel therapeutics. Here we describe in vivo visualization of fine structures within the feline brain that were previously only visible post mortem. NEW

method3Tesla MR images were acquired using T1-weighted (T1w) 3D magnetization-prepared rapid gradient echo (MPRAGE) sequence (0.4mm isotropic resolution) and T2-weighted (T2w) turbo spin echo (TSE) images (0.3mm×0.3mm×1mm resolution). Anatomic structures were identified based on feline and canine histology.

resultsT2w high resolution MR images with detailed structural identification are provided in transverse, sagittal and dorsal planes. T1w MR images are provided electronically in three dimensions for unrestricted spatial evaluation. COMPARISON WITH EXISTING

methodsMany areas of the feline brain previously unresolvable on MRI are clearly visible in three orientations, including the dentate, interpositus and fastigial cerebellar nuclei, cranial nerves, lateral geniculate nucleus, optic radiation, cochlea, caudal colliculus, temporal lobe, precuneus, spinocerebellar tract, vestibular nuclei, reticular formation, pyramids and rostral and middle cerebral arteries. Additionally, the feline brain is represented in three dimensions for the first time.

conclusionsThese data establish normal appearance of detailed anatomical structures of the feline brain, which provide reference when evaluating neurologic disease or testing efficacy of novel therapeutics in animal models.

Indexed as

AnimalsBrainCatsImaging, Three-DimensionalMagnetic Resonance ImagingMaleAnimal modelBrainCatCentral nervous systemMRITranslational

Identifiers

PMID24525327
PMCPMC4060963
OpenAlexW1994513909

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.