Evidence map›Paper›PMID 24525172›Full record

ReviewTrends in biotechnology2014

Point-of-care technologies for molecular diagnostics using a drop of blood.

Yujun Song, Yu-Yen Huang, Xuewu Liu, Xiaojing Zhang, Mauro Ferrari, Lidong Qin

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Trends in biotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. A Wearable In-Pad Diagnostic for the Detection of Disease Biomarkers in Menstruation Blood.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Engineering Innovative Interfaces for Point-of-Care Diagnostics.Current opinion in colloid & interface science · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yujun SongDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA; Department of Cell and Developmental Biology, Weill Medical College of Cornell University, New York, NY 10065, USA.
Yu-Yen HuangDepartment of Biomedical Engineering, University of Texas at Austin, Austin, TX 78758, USA.
Xuewu LiuDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA; Department of Cell and Developmental Biology, Weill Medical College of Cornell University, New York, NY 10065, USA.
Xiaojing ZhangDepartment of Biomedical Engineering, University of Texas at Austin, Austin, TX 78758, USA.
Mauro FerrariDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA; Department of Cell and Developmental Biology, Weill Medical College of Cornell University, New York, NY 10065, USA.
Lidong QinDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA; Department of Cell and Developmental Biology, Weill Medical College of Cornell University, New York, NY 10065, USA. Electronic address: Lqin@HoustonMethodist.org.

Funding

Development of a Point-of-Care Volumetric Bar-Chart Chip for Drug QuantitationR01DA035868 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI QIN, LIDONG, WANG, PING · 2013 to 2020
$4.3M
(PQA4) Point-of-Care Test of Exposure to Hepatocellular Carcinoma Risk by V-ChipR01CA180083 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI QIN, LIDONG, WU, XIFENG · 2013 to 2016
$2.1M
NCI NIH HHS R01 CA180083NIDA NIH HHS R01 DA035868
6 · The paper itself

Abstract

Molecular diagnostics is crucial for prevention, identification, and treatment of disease. Traditional technologies for molecular diagnostics using blood are limited to laboratory use because they rely on sample purification and sophisticated instruments, are labor and time intensive, expensive, and require highly trained operators. This review discusses the frontiers of point-of-care (POC) diagnostic technologies using a drop of blood obtained from a finger prick. These technologies, including emerging biotechnologies, nanotechnologies, and microfluidics, hold the potential for rapid, accurate, and inexpensive disease diagnostics.

Indexed as

BiomarkersBlood Chemical AnalysisEnzyme-Linked Immunosorbent AssayHumansPoint-of-Care SystemsBiomarkersbiomoleculescirculating tumor cellsmolecular diagnosticsnucleic acidspoint-of-care diagnosticsproteins

Identifiers

PMID24525172
PMCPMC3962833

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.