Trial reportAJNR. American journal of neuroradiology2014
Diffusion-weighted imaging score of the brain stem: A predictor of outcome in acute basilar artery occlusion treated with the Solitaire FR device.
Trial report in AJNR. American journal of neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Endovascular treatment versus medical management for basilar artery occlusion with low-to-moderate symptoms (National Institutes of Health Stroke Scale < 10).European stroke journal · 2025Article
- Transverse diameter of brainstem infarction is a strong predictor of miserable outcome after mechanical thrombectomy for acute basilar artery occlusion.Scientific reports · 2024Article
- Mechanical thrombectomy for acute posterior cerebral artery stroke; Feasibility and predictors of outcome.Neuroradiology · 2022Article
- Predictive value of DWI posterior-circulation lesion volume for 90-day clinical outcome after endovascular treatment of acute basilar artery occlusion: a retrospective single-center study.Neuroradiology · 2022Article
- Endovascular Treatment for Posterior Circulation Stroke: Ways to Maximize Therapeutic Efficacy.Journal of stroke · 2022Review
- Neutrophil Count Predicts Malignant Cerebellar Edema and Poor Outcome in Acute Basilar Artery Occlusion Receiving Endovascular Treatment: A Nationwide Registry-Based Study.Frontiers in immunology · 2022Article
- Age and discharge modified Rankin score are associated with 90-Day functional outcome after basilar artery occlusion treated with endovascular therapy.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021Article
- A New Angiographic Collateral Grading System for Acute Basilar Artery Occlusion Treated with Endovascular Therapy.Translational stroke research · 2021Article
- Expanding controlled donation after the circulatory determination of death: statement from an international collaborative.Intensive care medicine · 2021Article
- Predictive value on diffusion weighted imaging scores for basilar artery occlusion after endovascular treatment.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021Article
- Prognostic Structural Neural Markers of MRI in Response to Mechanical Thrombectomy for Basilar Artery Occlusion.Frontiers in neurology · 2021Article
- Comatose With Basilar Artery Occlusion: Still Odds of Favorable Outcome With Recanalization Therapy.Frontiers in neurology · 2021Article
- Predictors of Very Poor Outcome after Mechanical Thrombectomy for Acute Basilar Artery Occlusion.Neurologia medico-chirurgica · 2020Article
- Predictors of Favorable Outcome after Endovascular Thrombectomy in MRI: Selected Patients with Acute Basilar Artery Occlusion.AJNR. American journal of neuroradiology · 2020Article
- Basilar Artery Occlusion: Diagnosis and Acute Treatment.Current treatment options in neurology · 2019Review
- DWI-pc-ASPECT score in basilar artery occlusion: is 6 points or less always indicative of a bad outcome?Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2019Article
- Endovascular Thrombectomy for Acute Basilar Artery Occlusion: A Multicenter Retrospective Observational Study.Journal of the American Heart Association · 2018Observational
- Imaging assessment of acute ischaemic stroke: a review of radiological methods.The British journal of radiology · 2018Review
- Revolution in acute ischaemic stroke care: a practical guide to mechanical thrombectomy.Practical neurology · 2017Review
- Neuroimaging Predictors of Clinical Outcome in Acute Basilar Artery Occlusion.Frontiers in neurology · 2017Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe prognosis for ischemic stroke due to acute basilar artery occlusion is very poor: Early recanalization remains the main factor that can improve outcomes. The baseline extent of brain stem ischemic damage can also influence outcomes. We evaluated the validity of an easy-to-use DWI score to predict clinical outcome in patients with acute basilar artery occlusion treated by mechanical thrombectomy. MATERIALS AND
methodsWe analyzed the baseline clinical and DWI parameters of 31 patients with acute basilar artery occlusion, treated within 24 hours of symptom onset by using a Solitaire FR device. The DWI score of the brain stem was assessed with a 12-point semiquantitative score that separately considered each side of the medulla, pons, and midbrain. Clinical outcome was assessed at 180 days by using the mRS. According to receiver operating characteristic analyses, the cutoff score determined the optimal positive predictive value for outcome. The Spearman rank correlation coefficient assessed the correlation between the DWI brain stem score and baseline characteristics.
resultsSuccessful recanalization (Thrombolysis in Cerebral Infarction 3-2b) was achieved in 23 patients (74%). A favorable outcome (mRS ≤ 2) was observed in 11 patients (35%). An optimal DWI brain stem score of <3 predicted a favorable outcome. The probability of a very poor outcome (mRS ≥ 5) if the DWI brain stem score was ≥5 reached 80% (positive predictive value) and 100% if this score was ≥6. Interobserver reliability of the DWI brain stem score was excellent, with an intraclass correlation coefficient of 0.97 (95% CI, 0.96-0.99). The DWI brain stem score was significantly associated with baseline tetraplegia (P = .001) and coma (P = .005).
conclusionsIn patients with acute basilar artery occlusion treated by mechanical thrombectomy, the baseline DWI brain lesion score seems to predict clinical outcome.
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