Evidence map›Paper›PMID 24524526›Full record

ArticleAmerican journal of public health2014

Life course socioeconomic status and longitudinal accumulation of allostatic load in adulthood: multi-ethnic study of atherosclerosis.

Sharon Stein Merkin, Arun Karlamangla, Ana V Diez Roux, Sandi Shrager, Teresa E Seeman

Abstract read
In one paragraph

Article in American journal of public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Intergenerational Social Mobility and Allostatic Load in Midlife and Older Ages: A Diagonal Reference Modeling Approach.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023
    Article
  11. Cardiometabolic Risk Trajectory Among Older Americans: Findings From the Health and Retirement Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Change in Cardiometabolic Risk Among Blacks, Whites, and Hispanics: Findings From the Health and Retirement Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sharon Stein MerkinAt the time of this study, Sharon Stein Merkin, Arun Karlamangla, and Teresa E. Seeman were with the Division of Geriatrics, Geffen School of Medicine, University of California, Los Angeles. Ana V. Diez Roux was with the Department of Epidemiology, University of Michigan, Ann Arbor. Sandi Shrager was with the Department of Biostatistics, University of Washington School of Public Health, Seattle.
Arun Karlamangla
Ana V Diez Roux
Sandi Shrager
Teresa E Seeman

Funding

Institute for Clinical and Translational Research (UL1)UL1RR025005 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$75.8M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024156 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2006 to 2011
$53.0M
Stress, Gene-Environment Interaction and Cardiovascular DiseaseR01HL101161 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DIEZ ROUX, ANA VICTORIA, NEEDHAM, BELINDA L. · 2010 to 2013
$4.1M
SUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC095166 · HC · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI TRACY, RUSSELL P · 1999 to 2001
$758k
SUBCLINICAL CARDIOVASCULAR DISEASE COORDINATING CENTER-N01HC95159-268095159N01HC095159 · HC · UNIVERSITY OF WASHINGTON · PI KRONMAL, RICHARD A · 1999 to 2006
$304k
2009 Nitric Oxide Gordon Research ConferenceR13HL095166 · NHLBI · GORDON RESEARCH CONFERENCES · PI STUEHR, DENNIS J · 2009 to 2009
$15k
NCRR NIH HHS UL1 RR024156NCRR NIH HHS UL1-RR-024156NCRR NIH HHS UL1 RR025005NCRR NIH HHS UL1-RR-025005NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01-HC-95159NHLBI NIH HHS N01-HC-95166NHLBI NIH HHS R01 HI101161NHLBI NIH HHS R01 HL101161
6 · The paper itself

Abstract

objectivesWe examined the association of childhood and adult socioeconomic status with longitudinal change in allostatic load (AL), a measure of biological dysfunction.

methodsThe study sample included 6135 participants from the Multi-Ethnic Study of Atherosclerosis, aged 45 to 84 years, recruited in 2000 from 6 US counties; 3 follow-up examinations took place through September 2011. We calculated standardized scores for several metabolic and cardiovascular components relative to accepted clinical cut points for "higher risk" and then summed them to create an overall index of AL. We used mixed effects growth curve models to assess the relationship between socioeconomic status and AL as a linear function of time passed since the baseline examination; we included random effects for the intercept and slope.

resultsAmong those with lower baseline AL (< median), high adult education was associated with a significantly slower increase in AL over time, whereas there was no significant association among those with higher baseline AL.

conclusionsThe relationship between socioeconomic status and patterns of change in health parameters may vary over time and with the accumulation of biological risk.

Indexed as

AllostasisAgedAged, 80 and overAtherosclerosisEthnicityFemaleHumansMaleMiddle AgedProspective StudiesRisk FactorsSocioeconomic FactorsUnited States

Identifiers

PMID24524526
PMCPMC4025706

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.