Evidence map›Paper›PMID 24524449›Full record

ReviewClinics in perinatology2014

Fault and blame, insults to the perinatal brain may be remote from time of birth.

Sidhartha Tan

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Delayed intranasal infusion of human amnion epithelial cells improves white matter maturation after asphyxia in preterm fetal sheep.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Sidhartha TanNorthShore University Health System, University Chicago Pritzker School of Medicine, 2650 Ridge Avenue, Evanston, IL 60201, USA. Electronic address: sidtan@uchicago.edu.

Funding

Perinatal white matter development and fetal hypoxiaR01NS051402 · NINDS · NORTHSHORE UNIVERSITY HEALTHSYSTEM · PI TAN, SIDHARTHA · 2006 to 2010
$2.2M
Reactive nitrogen species in hypoxic fetal brain injuryR01NS043285 · NINDS · NORTHSHORE UNIV HEALTHSYSTEM RES INST · PI TAN, SIDHARTHA · 2003 to 2007
$2.1M
Neuronal nitric oxide synthase in early critical fetal brain injury from hypoxiaR56NS043285 · NINDS · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI TAN, SIDHARTHA · 2010 to 2010
$493k
Developing a preventive cure for cerebral palsyR21NS063141 · NINDS · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI TAN, SIDHARTHA · 2009 to 2010
$325k
NINDS NIH HHS R01 NS043285NINDS NIH HHS R01 NS051402NINDS NIH HHS R21 NS063141NINDS NIH HHS R56 NS043285
6 · The paper itself

Abstract

There is a certainty in malpractice cases that neurodevelopmental deficits are caused by preventable events at birth when the onset, nature, and timing of the insult in the antenatal and natal period are unknown. The biggest problem is determining timing. Electronic fetal monitoring is given excessive importance in legal cases. Before assigning fault on events at birth, a better understanding of developmental neurobiology and limitations of the present clinical biomarkers is warranted. The issues of single versus repeated episodes, timing of antenatal insults, pros and cons of legal arguments, interaction of various etiologic and anatomic factors are discussed.

Indexed as

Acid-Base ImbalanceBacteremiaBirth InjuriesBrainBrain InjuriesCerebral PalsyEnterocolitis, NecrotizingFemaleHumansHypoxia-Ischemia, BrainInfant, NewbornMagnetic Resonance ImagingObstetricsPregnancyPrenatal InjuriesTime FactorsAnoxiaAntenatalBirthBrainCerebral palsyFetusNewborn

Identifiers

PMID24524449
PMCPMC11908706

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.