Evidence map›Paper›PMID 24524023›Full record

ArticleOsong public health and research perspectives2013

Development of a Specific and Rapid Diagnostic Method for Detecting Influenza A (H1N1) pdm09 Virus Infection Using Immunochromatographic Assay.

Mi Jung Ji, Byung Ki Cho, Young Shik Cho, Young Jin Choi, Donghyok Kwon, Kyeongcheol Shin, Joo-Yeon Lee, Chun Kang, Byoung Su Yoon

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Osong public health and research perspectives, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mi Jung JiBiotech Laboratory, Standard Diagnostics Inc., Yongin, Korea ; Department of Life Science, College of Natural Science, Kyonggi University, Suwon, Korea.
Byung Ki ChoBiotech Laboratory, Standard Diagnostics Inc., Yongin, Korea.
Young Shik ChoBiotech Laboratory, Standard Diagnostics Inc., Yongin, Korea.
Young Jin ChoiDepartment of Laboratory Medicine, College of Medicine, Soonchunhyang University, Cheonan, Korea.
Donghyok KwonDivision of Influenza Virus, Korea National Institute of Health, Osong, Korea.
Kyeongcheol ShinDivision of Influenza Virus, Korea National Institute of Health, Osong, Korea.
Joo-Yeon LeeDivision of Influenza Virus, Korea National Institute of Health, Osong, Korea.
Chun KangDivision of Influenza Virus, Korea National Institute of Health, Osong, Korea.
Byoung Su YoonDepartment of Life Science, College of Natural Science, Kyonggi University, Suwon, Korea.
Korea National Institute of Health · KRKyonggi University · KRSoonchunhyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to develop an immunochromatographic assay (ICA) for the detection of influenza A (H1N1) pdm09 virus infection. MATERIALS AND

methodsSeveral monoclonal antibodies against influenza A (H1N1) pdm09 virus were generated and an ICA (pdm09-ICA) was developed for the rapid and specific detection of influenza A (H1N1) pdm09 virus infection. The specificity and sensitivity of the developed assay were compared with that of hemagglutination assay and real-time reverse-transcription polymerase chain reaction (rRT-PCR).

resultsThe detection limit was estimated to be 1/2 (8) hemagglutinating unit; the sensitivity and specificity rates of pdm09-ICA were 75.86% (110/145) and 100% (43/43), respectively, compared with rRT-PCR. The cross-reactivity for 20 influenza viruses, including seasonal H1N1 viruses, was found to be negative except for the H1N1 virus (A/Swine/Korea/GC0503/2005).

conclusionThese results indicate that the proposed method can be easily used for rapid and specific detection of the pdm09 infection. The assay developed in this study would be a useful tool for distinguishing the pdm09 infection from seasonal influenza A and B infections.

Indexed as

immunochromatographic assayimmunochromatography testinfluenzapdm09

Identifiers

PMID24524023
PMCPMC3922102
OpenAlexW2144558555

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.