ArticleAvicenna journal of medical biotechnology2014
Fourier transform infrared spectroscopy: a potential technique for noninvasive detection of spermatogenesis.
Article in Avicenna journal of medical biotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Metabolomics of Human Semen: A Review of Different Analytical Methods to Unravel Biomarkers for Male Fertility Disorders.International journal of molecular sciences · 2022Review
- Fast diagnosis of men's fertility using Raman spectroscopy combined with chemometric methods: An experimental study.International journal of reproductive biomedicine · 2021Article
- The Personalization of Clopidogrel Antiplatelet Therapy: The Role of Integrative Pharmacogenetics and Pharmacometabolomics.Cardiology research and practice · 2017Review
- Male Infertility, Precision Medicine and Systems Proteomics.Journal of reproduction & infertilityReview
- Metabolomics of Male Infertility: A New Tool for Diagnostic Tests.Journal of reproduction & infertilityReview
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe seminal plasma is an excellent source for noninvasive detection of spermatogenesis. The seminal plasma of normospermic and azoospermic men has been analyzed for detection of spermatogenesis.
methodsOptical spectroscopy (Attenuated Total Reflectance-Infrared spectroscopy (ATR-IR) and Fourier Transform infrared spectroscopy (FT-IR) has been used to analyze the seminal plasma and the metabolome of seminal plasma for detection of spermatogenesis.
resultsThe seminal plasma of normospermic and azoospermic men has been analyzed by ATR-IR. The results show that there is a pattern variation in the azoospermic men compared to normospermic men. However, the seminal plasma is too complex to show significant pattern variation. Therefore, the metabolome which is a subcomponent of the seminal plasma was analyzed. The seminal plasma metabolome of normospermic and azoospermic men has been analyzed by FT-IR. A significant pattern change was observed. The data combined with chemometrics analysis showed that significant changes are observed at metabolome level.
conclusionWe suggest that FT-IR has the potential as a diagnostic tool instead of testicular biopsy.
Indexed as
Identifiers
24523955PMC3895579What OpenQuestion holds
Registered trials
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