ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2013
Resistance pattern of Helicobacter pylori strains to clarithromycin, metronidazole, and amoxicillin in Isfahan, Iran.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- The prevalence of clarithromycin-resistantPeerJ · 2023Pooled it
- Assessment ofMicroorganisms · 2026Article
- Antibiotic Resistance Identification Among the Patients withMiddle East journal of digestive diseases · 2025Article
- Effects of 14-days bismuth- and tetracycline-containing quadruple therapy with concomitant regimen for the first lineCaspian journal of internal medicine · 2023Article
- Evaluation of antibiotic resistance of Helicobacter pylori bacteria obtained from gastric biopsy samples: A cohort study.Annals of medicine and surgery (2012) · 2022Article
- The efficacy and safety of furazolidone-bismuth quadruple therapy forGastroenterology and hepatology from bed to bench · 2022Article
- Antibiotic resistance pattern ofJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022Article
- Molecular Assessment of Resistance to Clarithromycin inBioMed research international · 2020Article
- Bacterial infections are associated with cardiovascular disease in Iran: a meta-analysis.Archives of medical science : AMS · 2019Article
- The Interaction ofAdvanced biomedical research · 2019Review
- Genetic basis for metronidazole and clarithromycin resistance inInfection and drug resistance · 2019Article
- Eradication ofMiddle East journal of digestive diseases · 2018Review
- Furazolidone, an Underutilized Drug for H. pylori Eradication: Lessons from Iran.Digestive diseases and sciences · 2017Review
- Article
- Treatment of Helicobacter pylori infection: Current and future insights.World journal of clinical cases · 2016Review
- Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2016Article
- Multicenter Study of Antibiotic Resistance Profile of H. pylori and Distribution of CYP2C19 Gene Polymorphism in Rural Population of Chongqing, China.Gastroenterology research and practice · 2016Article
- Prevalence of antibiotic resistance in Helicobacter pylori: A recent literature review.World journal of methodology · 2015Review
- How to Effectively Use Bismuth Quadruple Therapy: The Good, the Bad, and the Ugly.Gastroenterology clinics of North America · 2015Review
- Efficacy of Clarithromycin Containing Bismuth-Based Regimen as a Second-Line Therapy in Helicobacter Pylori Eradication.Middle East journal of digestive diseases · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHelicobacter pylori (H. pylori) resistance to antibiotics has become a global problem and is an important factor in determining the outcome of treatment of infected patients. The purpose of this study was to determine the H. pylori resistance to clarithromycin, metronidazole, and amoxicillin in gastrointestinal disorders patients. MATERIALS AND
methodsIn this study, a total of 260 gastric antrum biopsy specimens were collected from patients with gastrointestinal disorders who referred to Endoscopy Section of the Isfahan Hospitals. The E-test and Modified Disk Diffusion Method (MDDM) were used to verify the prevalence of antibiotic resistance in 78 H. pylori isolates to the clarithromycin, metronidazole, and amoxicillin.
resultsH. pylori resistance to clarithromycin, metronidazole, and amoxicillin were 15.3, 55.1, and 6.4%, respectively. In this study, we had one multidrug resistance (MDR) isolates from patient with gastritis and peptic ulcer disease.
conclusionInformation on antibiotic susceptibility profile plays an important role in empiric antibiotic treatment and management of refractive cases. According to the results obtained in this study, H. pylori resistance to clarithromycin and metronidazole was relatively high. MDR strains are emerging and will have an effect on the combination therapy.
Indexed as
Identifiers
24523796PMC3908526W2169352687What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.