Evidence map›Paper›PMID 24523692›Full record

ArticleFrontiers in neuroinformatics2014

ACQ4: an open-source software platform for data acquisition and analysis in neurophysiology research.

Luke Campagnola, Megan B Kratz, Paul B Manis

Abstract read
In one paragraph

Article in Frontiers in neuroinformatics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Article
  3. Activation of 5-HTPharmacological reports : PR · 2024
    Article
  4. Article
  5. Cell class-specific electric field entrainment of neural activity.bioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
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  12. Review
  13. Article
  14. Article
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  16. Article
  17. Article
  18. Article
  19. Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luke CampagnolaDepartment of Otolaryngology/Head and Neck Surgery, Curriculum in Neurobiology, University of North Carolina at Chapel Hill Chapel Hill, NC, USA.
Megan B KratzDepartment of Otolaryngology/Head and Neck Surgery, Curriculum in Neurobiology, University of North Carolina at Chapel Hill Chapel Hill, NC, USA.
Paul B ManisDepartment of Otolaryngology/Head and Neck Surgery, Curriculum in Neurobiology, University of North Carolina at Chapel Hill Chapel Hill, NC, USA.

Funding

RESEARCH TRAINING IN THE NEUROSCIENCEST32NS007431 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Juan Song, Mark J. Zylka · 1997 to 2026
$10.0M
CELLULAR MECHANISMS OF AUDITORY INFORMATION PROCESSINGR01DC004551 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MANIS, PAUL B · 2000 to 2018
$5.9M
PHYSIOLOGY OF DORSAL COCHLEAR NUCLEUS MOLECULAR LAYERR01DC000425 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MANIS, PAUL B · 1989 to 2011
$3.0M
Auditory Cortex: Synaptic organization and plasticityR01DC009809 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MANIS, PAUL B · 2011 to 2015
$2.0M
Mapping the Connectivity of Cochlear Nucleus Bushy CellsF31DC010320 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CAMPAGNOLA, LUKE · 2010 to 2011
$63k
NIDCD NIH HHS F31 DC010320NIDCD NIH HHS R01 DC000425NIDCD NIH HHS R01 DC004551NIDCD NIH HHS R01 DC009809NINDS NIH HHS T32 NS007431
6 · The paper itself

Abstract

The complexity of modern neurophysiology experiments requires specialized software to coordinate multiple acquisition devices and analyze the collected data. We have developed ACQ4, an open-source software platform for performing data acquisition and analysis in experimental neurophysiology. This software integrates the tasks of acquiring, managing, and analyzing experimental data. ACQ4 has been used primarily for standard patch-clamp electrophysiology, laser scanning photostimulation, multiphoton microscopy, intrinsic imaging, and calcium imaging. The system is highly modular, which facilitates the addition of new devices and functionality. The modules included with ACQ4 provide for rapid construction of acquisition protocols, live video display, and customizable analysis tools. Position-aware data collection allows automated construction of image mosaics and registration of images with 3-dimensional anatomical atlases. ACQ4 uses free and open-source tools including Python, NumPy/SciPy for numerical computation, PyQt for the user interface, and PyQtGraph for scientific graphics. Supported hardware includes cameras, patch clamp amplifiers, scanning mirrors, lasers, shutters, Pockels cells, motorized stages, and more. ACQ4 is available for download at http://www.acq4.org.

Indexed as

analysis softwarecalcium imagingdata acquisitionelectrophysiologylaser scanning photostimulationmultiphoton microscopypatch clamppython language

Identifiers

PMID24523692
PMCPMC3906568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.