SynthesisBMJ open2014
Associations between environmental exposures and asthma control and exacerbations in young children: a systematic review.
Synthesis in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- Update of a systematic review on associations between environmental exposures and asthma control and exacerbations in young children.BMJ open · 2025Pooled it
- A systematic review of associations between environmental exposures and development of asthma in children aged up to 9 years.BMJ open · 2014Pooled it
- Climate change, environmental exposures, and pediatric asthma exacerbations: air pollution, temperature, and relative humidity.Pediatric research · 2026Review
- Characterising the allergen landscape in paediatric allergic rhinitis and/or asthma.BMJ open respiratory research · 2026Article
- Determinants of Asthma Control in Jordanian Children: The Role of Comorbidities and FeNO Levels.Children (Basel, Switzerland) · 2025Article
- Article
- How Families Manage the Home Environment for Young People With Asthma and Allergic Sensitisation: A Qualitative Study.Pediatric pulmonology · 2025Article
- Effect of high-efficiency particulate air filter on children with asthma: a systematic review protocol of RCTs.BMJ open · 2024Article
- Exploring the Relationship between Wind Patterns and Hospital Admissions Due to Respiratory Symptoms in Children.Children (Basel, Switzerland) · 2024Article
- A Roadmap for Using Causal Inference and Machine Learning to Personalize Asthma Medication Selection.JMIR medical informatics · 2024Article
- Safety of subcutaneous immunotherapy with Novo-Helisen-Depot in the children: a retrospective analysis from a single center in Northern China.Frontiers in pediatrics · 2024Article
- Effect of cold winters on the risk of new asthma: a case-crossover study in Finland.Occupational and environmental medicine · 2023Article
- Trajectories of neighborhood environmental factors and their associations with asthma symptom trajectories among children in Australia: evidence from a national birth cohort study.Journal of environmental health science & engineering · 2022Article
- Article
- Assessment of level of asthma control and related factors in children attending pediatric respiratory clinics in Addis Ababa, Ethiopia.BMC pulmonary medicine · 2022Article
- Environmental effects on acute exacerbations of respiratory diseases: A real-world big data study.The Science of the total environment · 2022Article
- Study Protocol to Determine Association between Environmental Triggers and Asthma among Children in King Williams Town.Methods and protocols · 2021Article
- Defining pediatric asthma: phenotypes to endotypes and beyond.Pediatric research · 2021Review
- Using Computational Methods to Improve Integrated Disease Management for Asthma and Chronic Obstructive Pulmonary Disease: Protocol for a Secondary Analysis.JMIR research protocols · 2021Article
- Children's Environmental Health: A Systems Approach for Anticipating Impacts from Chemicals.International journal of environmental research and public health · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo complete a systematic review of the literature describing associations between all environmental exposures and asthma symptoms and exacerbations in children up to mean age of 9 years.
designSystematic review.
settingReference lists of identified studies and reviews were searched for all articles published until November 2013 in electronic databases (MEDLINE, EMBASE, CINAHL, Cochrane Controls Trials Register).
participantsStudies were selected which examined a link between exposure to environmental factors and asthma symptoms and exacerbations where the study participants were children with a mean age of ≤9 years. PRIMARY AND SECONDARY OUTCOME MEASURES: Indices of asthma symptoms, control and exacerbations.
resultsA total of 27 studies were identified including eight where inhaled allergens and four where environmental tobacco smoke (ETS) were the exposures of interest. There was evidence that exposure to allergen, ETS, poor air quality and unflued heaters had a modest magnitude of effect (ORs between 2 and 3). There was also evidence of interactions observed between exposures such as allergen and ETS.
conclusionsExposure to inhaled allergens, ETS, unflued heaters and poor air quality has an important effect on exacerbations in young children with asthma and should be minimised or, ideally, avoided. Better understanding of the effect of exposure to damp housing, air conditioning and dietary factors plus interactions between environmental exposures associated with exacerbations is required.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.