ArticleHuman brain mapping2014
Prognostic value of changes in resting-state functional connectivity patterns in cognitive recovery after stroke: A 3T fMRI pilot study.
Article in Human brain mapping, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Resting-state functional connectivity alterations in post-stroke cognitive impairment: a systematic review.Brain imaging and behavior · 2025Pooled it
- Effects of multi-site non-invasive brain stimulation on cognitive impairment after stroke: a systematic review and meta-analysis.Frontiers in human neuroscience · 2025Pooled it
- Dual Transcranial Direct Current Stimulation Modulates Hierarchical Functional Network Organization in Post-Stroke Cognitive Impairment: A Randomized Controlled Trial.CNS neuroscience & therapeutics · 2026Trial
- Vocal music enhances memory and language recovery after stroke: pooled results from two RCTs.Annals of clinical and translational neurology · 2020Trial
- Lateralization-specific motor network reorganization in pontine infarction revealed by resting-state functional connectivity magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2026Article
- The Cerebellar Connectome Disruptions in Ischemic Stroke.CNS neuroscience & therapeutics · 2026Article
- Differential Abnormality in Regional Brain Spontaneous Activity and Functional Connectivity in Patients of Non-Acute Subcortical Stroke With Versus Without Global Cognitive Functional Impairment.Brain and behavior · 2025Article
- Flow augmentation therapies preserve brain network integrity and hemodynamics in a canine permanent occlusion model.Scientific reports · 2024Article
- Structural brain networks correlating with poststroke cognition.Human brain mapping · 2024Observational
- Association of aberrant structural-functional network coupling with cognitive decline in patients with non-dialysis-dependent stage 5 chronic kidney disease.Quantitative imaging in medicine and surgery · 2023Article
- Brain network analysis reveals convergent and divergent aberrations between mild stroke patients with cortical and subcortical infarcts during cognitive task performing.Frontiers in aging neuroscience · 2023Article
- Research and application advances in rehabilitation assessment of stroke.Journal of Zhejiang University. Science. B · 2022Review
- Distinct brain structural-functional network topological coupling explains different outcomes in tinnitus patients treated with sound therapy.Human brain mapping · 2022Article
- Abnormal cerebellar network and effective connectivity in sudden and long-term sensorineural hearing loss.Frontiers in aging neuroscience · 2022Article
- Resting-State Beta-Band Recovery Network Related to Cognitive Improvement After Stroke.Frontiers in neurology · 2022Article
- The disrupted topological properties of structural networks showed recovery in ischemic stroke patients: a longitudinal design study.BMC neuroscience · 2021Article
- Differentiation of Cerebellum-Type and Parkinson-Type of Multiple System Atrophy by Using Multimodal MRI Parameters.Frontiers in aging neuroscience · 2021Article
- Indexing brain state-dependent pupil dynamics with simultaneous fMRI and optical fiber calcium recording.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Altered Prefrontal-Basal Ganglia Effective Connectivity in Patients With Poststroke Cognitive Impairment.Frontiers in neurology · 2020Article
- Pattern Recognition to Identify Stroke in the Cognitive Profile: Secondary Analyses of a Prospective Cohort Study.Cerebrovascular diseases extra · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 2 countries.
Funding
Abstract
Resting-state studies conducted with stroke patients are scarce. First objective was to explore whether patients with good cognitive recovery showed differences in resting-state functional patterns of brain activity when compared to patients with poor cognitive recovery. Second objective was to determine whether such patterns were correlated with cognitive performance. Third objective was to assess the existence of prognostic factors for cognitive recovery. Eighteen right-handed stroke patients and eighteen healthy controls were included in the study. Stroke patients were divided into two groups according to their cognitive improvement observed at three months after stroke. Probabilistic independent component analysis was used to identify resting-state brain activity patterns. The analysis identified six networks: frontal, fronto-temporal, default mode network, secondary visual, parietal, and basal ganglia. Stroke patients showed significant decrease in brain activity in parietal and basal ganglia networks and a widespread increase in brain activity in the remaining ones when compared with healthy controls. When analyzed separately, patients with poor cognitive recovery (n=10) showed the same pattern as the whole stroke patient group, while patients with good cognitive recovery (n=8) showed increased activity only in the default mode network and fronto-temporal network, and decreased activity in the basal ganglia. We observe negative correlations between basal ganglia network activity and performance in Semantic Fluency test and Part A of the Trail Making Test for patients with poor cognitive recovery. A reverse pattern was observed between frontal network activity and the above mentioned tests for the same group. .
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.