Evidence map›Paper›PMID 24523007›Full record

Trial reportAIDS and behavior2014

HPTN 062: a feasibility and acceptability pilot intervention to reduce HIV transmission risk behaviors among individuals with acute and early HIV infection in Lilongwe, Malawi.

Amy Corneli, Audrey Pettifor, Gift Kamanga, Carol Golin, Kevin McKenna, San-San Ou, Gloria Hamela, Cecelia Massa, Francis Martinson, Jenae Tharaldson and 5 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Understanding of Perceived Infectiousness and Its Influence on Sexual Behavior Among Individuals With Acute HIV Infection in Lilongwe, Malawi (HPTN 062).AIDS education and prevention : official publication of the International Society for AIDS Education · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Amy CorneliSocial and Behavioral Health Sciences, FHI 360, 359 Blackwell St, Suite 200, Durham, NC, 27701, USA, acorneli@fhi360.org.
Audrey Pettifor
Gift Kamanga
Carol Golin
Kevin McKenna
San-San Ou
Gloria Hamela
Cecelia Massa
Francis Martinson
Jenae Tharaldson
Deborah Hilgenberg
Xuesong Yu
Wairimu Chege
Irving Hoffman
HPTN 062 study team
University of North Carolina at Chapel Hill · USUniversity of Malawi · MWFamily Health International 360 · USDurham University · GBNational Institutes of Health · US

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI Sinead Delany-Moretlwe, RAPHAEL J LANDOVITZ · 2011 to 2026
$779.5M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Mentoring Junior Investigators: Comprehensive HIV PreventionK24HD069204 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GOLIN, CAROL E · 2013 to 2017
$789k
NIAID NIH HHS P30 AI050410NIAID NIH HHS UM1 AI068619NICHD NIH HHS K24 HD069204NICHD NIH HHS P2C HD050924
6 · The paper itself

Abstract

Acute HIV infection (AHI) is a relatively brief period of time when individuals are highly infectious and the opportunity to intervene to prevent forward transmission is extremely limited. HPTN 062 partnered with CHAVI 001 to evaluate the feasibility and acceptability of a motivational interviewing (MI)-based counseling intervention to reduce HIV-transmission risk behaviors among individuals with acute and early HIV infection in Lilongwe, Malawi. Participants were randomized to receive either (1) brief education sessions about HIV and AHI; or (2) the same brief education sessions plus an MI-based counseling intervention called Uphungu Wanga. Although Uphungu Wanga was determined to be feasible and acceptable, few major differences existed between the two arms with regard to acceptability, feasibility, and self-reported sexual behaviors. We therefore conclude that an additional MI-based counseling intervention may not be needed during the short period of AHI. Instead, we recommend that individuals with AHI receive frequent, but brief, counseling immediately after diagnosis and then transition to receiving counseling at less frequent intervals until they can initiate antiretroviral therapy. Other recommendations are provided.

Indexed as

CounselingPatient Acceptance of Health CareRisk-TakingSexual PartnersAcute DiseaseAdolescentAdultFeasibility StudiesFemaleHIV InfectionsHIV SeropositivityHumansMalawiMaleMotivational InterviewingPilot Projects

Identifiers

PMID24523007
PMCPMC4183128
OpenAlexW2090176568

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.