ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2014
Genetic analyses of BaMMV/BaYMV resistance in barley accession HOR4224 result in the identification of an allele of the translation initiation factor 4e (Hv-eIF4E) exclusively effective against Barley mild mosaic virus (BaMMV).
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Molecular gatekeepers: eukaryotic translation factors decoding plant-virus dynamics for resistance engineering.Stress biology · 2026Review
- Identification and characterization of a novel QTL for barley yellow mosaic disease resistance from bulbous barley.The plant genome · 2025Article
- A novel QTL qRYM-7H for barley yellow mosaic resistance identified by GWAS and linkage analysis.Plant molecular biology · 2024Article
- Genomic traces of Japanese malting barley breeding in two modern high-quality cultivars, 'Sukai Golden' and 'Sachiho Golden'.Breeding science · 2023Article
- Genome-Wide Identification and Expression Analysis of eIF Family Genes fromPlants (Basel, Switzerland) · 2022Article
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- High-Resolution Mapping ofFrontiers in plant science · 2022Article
- Delineating the elusive BaMMV resistance geneMolecular breeding : new strategies in plant improvement · 2021Article
- Identification of novel QTL contributing to barley yellow mosaic resistance in wild barley (Hordeum vulgare spp. spontaneum).BMC plant biology · 2021Article
- Genomic prediction models trained with historical records enable populating the German ex situ genebank bio-digital resource center of barley (Hordeum sp.) with information on resistances to soilborne barley mosaic viruses.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- High-resolution mapping of Rym14TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Use of Molecular Markers for Doubled Haploid Technology: From Academia to Plant Breeding Companies.Methods in molecular biology (Clifton, N.J.) · 2021Review
- Bymovirus-induced yellow mosaic diseases in barley and wheat: viruses, genetic resistances and functional aspects.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Review
- Bulked segregant RNA-sequencing (BSR-seq) identified a novel rare allele of eIF4E effective against multiple isolates of BaYMV/BaMMV.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- Sequence diversification in recessive alleles of two host factor genes suggests adaptive selection for bymovirus resistance in cultivated barley from East Asia.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Article
- Plant Translation Factors and Virus Resistance.Viruses · 2015Review
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8 authors.
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Abstract
key messageBased on a strategy combining extensive segregation analyses and tests for allelism with allele-specific re-sequencing an Hv-eIF4E allele exclusively effective against BaMMV was identified and closely linked markers for BaYMV resistance were developed. Soil-borne barley yellow mosaic disease is one of the most important diseases of winter barley. In extensive screenings for resistance, accession 'HOR4224' being resistant to three strains of Barley mild mosaic virus (BaMMV-ASL1, BaMMV-Sil, and BaMMV-Teik) and two strains of Barley yellow mosaic virus (BaYMV-1 and BaYMV-2) was identified. Analyses using Bmac29, being to some extent diagnostic for the rym4/5 locus, gave hint to the presence of the susceptibility-encoding allele at this locus. Therefore, 107 DH lines derived from the cross 'HOR4224' × 'HOR10714' (susceptible) were screened for resistance. Genetic analyses revealed an independent inheritance of resistance to BaMMV and BaYMV ([Formula: see text] = 5.58) both encoded by a single gene (BaMMV [Formula: see text] = 0.477; BaYMV [Formula: see text] = 0.770). Although Bmac29 indicated the susceptibility-encoding allele, BaMMV resistance of 'HOR4224' co-localized with rym4/rym5. The BaYMV resistance was mapped to chromosome 5H in the region of rym3. Sequencing of full length cDNA of the Hv-eIF4E gene displayed an already sequenced allele described to be efficient against BaMMV and BaYMV. However, the F1 progenies of crosses involving 'HOR4224' and rym4/rym5 donors were all resistant to BaMMV but susceptible to BaYMV. Therefore, this is the first report of an allele at the rym4/rym5 locus exclusively efficient against BaMMV. Changes in the specificity are due to one non-synonymous amino acid substitution (I118K). Results obtained elucidate that combining extensive segregation analyses and tests for allelism involving different strains of BaMMV/BaYMV in combination with allele-specific re-sequencing is an efficient strategy for gene and allele detection in complex pathosystems.
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