ArticleKidney international2014
Relative risks of chronic kidney disease for mortality and end-stage renal disease across races are similar.
Article in Kidney international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Guidelines for clinical evaluation of chronic kidney disease : AMED research on regulatory science of pharmaceuticals and medical devices.Clinical and experimental nephrology · 2018Guideline
- Pooled it
- Pooled it
- Kidney Function and Cardiovascular Events in Postmenopausal Women: The Impact of Race and Ethnicity in the Women's Health Initiative.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016Trial
- Ethnic Disparities in CKD Progression: A Comparative Study of CRIC and KNOW-CKD Cohorts.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Developments in albuminuria testing: A key biomarker for detection, prognosis and surveillance of kidney and cardiovascular disease-A practical update for clinicians.Diabetes, obesity & metabolism · 2025Review
- Carbamylated Albumin, Heart Failure, and Mortality in Patients Undergoing Coronary Angiography.Clinical chemistry · 2025Article
- The health-economic impact of urine albumin-to-creatinine ratio testing for chronic kidney disease in Japanese non-diabetic patients.Clinical and experimental nephrology · 2025Article
- Consequences of low estimated glomerular filtration rate either before or early after kidney donation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024Article
- Is There Still a Place to Study Race in the Nephrology Space?Kidney international reports · 2023Article
- Kidney Function and Long-Term Risk of End-Stage Kidney Disease and Mortality in a Multiethnic Population.Kidney international reports · 2023Article
- Vaccination and mortality from COVID-19: a comparative study between hemodialysis, peritoneal dialysis, and non-dialysis adult population in Panama.International urology and nephrology · 2023Article
- Article
- Epidemiology and risk of cardiovascular disease in populations with chronic kidney disease.Nature reviews. Nephrology · 2022Review
- Case-Fatality and Temporal Trends in Patients with Psoriasis and End-Stage Renal Disease.Journal of clinical medicine · 2022Article
- Cardiovascular complications after COVID-19 in chronic kidney disease, dialysis and kidney transplant patients.International urology and nephrology · 2022Review
- Article
- Presentation and outcome of chronic kidney disease in Italian and immigrant citizens: results from the Emilia-Romagna PIRP project.Journal of nephrology · 2022Article
- Risk Factors for Progression of CKD with and without Diabetes.Journal of diabetes research · 2022Article
- Non-diabetic end-stage renal disease in Saudis associated with polymorphism of MYH9 gene but not UMOD gene.Medicine · 2020Observational
Corrections and comments
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Authors and funding
15 authors at 13 institutions in 7 countries.
Funding
Abstract
Some suggest race-specific cutpoints for kidney measures to define and stage chronic kidney disease (CKD), but evidence for race-specific clinical impact is limited. To address this issue, we compared hazard ratios of estimated glomerular filtration rates (eGFR) and albuminuria across races using meta-regression in 1.1 million adults (75% Asians, 21% Whites, and 4% Blacks) from 45 cohorts. Results came mainly from 25 general population cohorts comprising 0.9 million individuals. The associations of lower eGFR and higher albuminuria with mortality and end-stage renal disease (ESRD) were largely similar across races. For example, in Asians, Whites, and Blacks, the adjusted hazard ratios (95% confidence interval) for eGFR 45-59 versus 90-104 ml/min per 1.73 m(2) were 1.3 (1.2-1.3), 1.1 (1.0-1.2), and 1.3 (1.1-1.7) for all-cause mortality, 1.6 (1.5-1.7), 1.4 (1.2-1.7), and 1.4 (0.7-2.9) for cardiovascular mortality, and 27.6 (11.1-68.7), 11.2 (6.0-20.9), and 4.1 (2.2-7.5) for ESRD, respectively. The corresponding hazard ratios for urine albumin-to-creatinine ratio 30-299 mg/g or dipstick 1+ versus an albumin-to-creatinine ratio under 10 or dipstick negative were 1.6 (1.4-1.8), 1.7 (1.5-1.9), and 1.8 (1.7-2.1) for all-cause mortality, 1.7 (1.4-2.0), 1.8 (1.5-2.1), and 2.8 (2.2-3.6) for cardiovascular mortality, and 7.4 (2.0-27.6), 4.0 (2.8-5.9), and 5.6 (3.4-9.2) for ESRD, respectively. Thus, the relative mortality or ESRD risks of lower eGFR and higher albuminuria were largely similar among three major races, supporting similar clinical approach to CKD definition and staging, across races.
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Registered trials
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