Evidence map›Paper›PMID 24521540›Full record

ArticleLiver international : official journal of the International Association for the Study of the Liver2015

Readiness for behaviour change in non-alcoholic fatty liver disease: implications for multidisciplinary care models.

Karen E Stewart, Deborah L Haller, Carol Sargeant, James L Levenson, Puneet Puri, Arun J Sanyal

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Liver international : official journal of the International Association for the Study of the Liver, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06348628 (Motivational Interviewing for Weight Loss in the Management of Non Alcoholic Fatty Liver Disease - A Randomized Controlled Trial), which is not on this map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06348628 nacompletednot on this mapstarted 2022, after this paper: background citation

Motivational Interviewing for Weight Loss in the Management of Non Alcoholic Fatty Liver Disease - A Randomized Controlled Trial

TypeinterventionalSponsorMadunil Anuk NiriellaRan2022 to 2025Enrolled231ConditionsNon-Alcoholic Fatty Liver DiseaseArmsMotivational Interview, Placebo
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
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  3. ESPEN guideline on clinical nutrition in liver disease.Clinical nutrition (Edinburgh, Scotland) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Karen E StewartDivision of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University School of Medicine, Richmond, VA, USA; Department of Psychiatry, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Deborah L Haller
Carol Sargeant
James L Levenson
Puneet Puri
Arun J Sanyal
Virginia Commonwealth University · USColumbia University · US

Funding

Center for Clinical and Translational ResearchUL1TR000058 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2012 to 2015
$12.5M
Training Grant in Digestive Diseases and Liver DiseasesT32DK007150 · NIDDK · VIRGINIA COMMONWEALTH UNIVERSITY · PI SANYAL, ARUN J · 1986 to 2017
$4.2M
MicroRNA in Liver DevelopmentR03DK081450 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI FRIEDMAN, JOSHUA R. · 2008 to 2009
$165k
NCATS NIH HHS UL1TR000058NIDDK NIH HHS R01 DK81450-04NIDDK NIH HHS R03 DK081450NIDDK NIH HHS T32 DK007150NIDDK NIH HHS T32 DK007150 36
6 · The paper itself

Abstract

BACKGROUND &

aimsWeight management is a cornerstone of treatment for overweight/obese persons with non-alcoholic fatty liver disease (NAFLD). This exploratory study sought to: (i) evaluate readiness to change weight-related behaviours; (ii) assess psychosocial characteristics that may interfere with weight loss; and (iii) evaluate how baseline psychosocial features associate with 6-month change in weight in persons with NAFLD receiving standard medical care. The purpose of this investigation was to develop hypotheses regarding relationships between psychosocial factors and weight for use in future fully powered studies and clinical interventions

methodsFifty-eight overweight/obese participants with NAFLD completed baseline measures of personality, psychiatric symptoms and readiness for behaviour change and were followed up for 6 months in standard care.

resultsOne-third of participants (31.0%) were not interested in making weight-related behaviour changes; 58.6% were considering making a change, and 10.4% of individuals were actively working on or preparing to change. Six-month change in weight was non-significant and was not associated with baseline readiness for change. Depression, low conscientiousness and high neuroticism were associated with higher weight at 6-month follow-up with small to large effect sizes.

conclusionsAlthough participants received nutritional education and guidance, very few individuals presented in the active stage of change. Although readiness for change did not predict subsequent change in weight, personality factors and psychiatric symptoms were associated with weight outcomes. Integrated multidisciplinary approaches that address psychiatric needs and provide behavioural support for weight loss may help patients with NAFLD implement sustained lifestyle changes.

Indexed as

Health BehaviorWeight Reduction ProgramsAdultBody Mass IndexFemaleHealth StatusHumansMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseObesityPilot ProjectsWeight LossNAFLDobesitypersonalitypsychiatric symptomsreadiness to change

Identifiers

PMID24521540
PMCPMC4266620
OpenAlexW2000723491

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.